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Recombinant Amphiregulin (AREG)

AR; CRDGF; SDGF; Colorectum Cell-Derived Growth Factor; Schwannoma-Derived Growth Factor

  • Product No.RPA006Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane; Single-pass membrane prote
  • Predicted Molecular Mass40.7kDa
  • Accurate Molecular Mass44kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer20~Asp100 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point5.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 160  US$ 400  US$ 800  US$ 2400  US$ 6000 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Onkologie Amphiregulin and Epiregulin Expression in Colorectal Carcinoma and the Correlation with Clinicopathological Characteristics Karger: 315380
Br J Cancer. Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer. Pubmed:24800946
Cancer Sci Association between serum ligands and the skin toxicity of anti-epidermal growth factor receptor antibody in metastatic colorectal cancer PubMed: 25707609
J Cancer Res Clin Oncol Amphiregulin confers trastuzumab resistance via AKT and ERK activation in HER2-positive breast cancer PubMed: 26195282
Oncotarget.  Serum level of hepatocyte growth factor is a novel marker of predicting theoutcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Pubmed:26716644
Acta Pharmacologica Sinica Anti-asthmatic activity of alkaloid compounds from Pericarpium Citri Reticulatae (Citrus reticulata 'Chachi') Pubmed: 19363516
International Journal of Biological Sciences CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17
Neoplasia Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine Pubmed: 33212364
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets Pubmed: 33164313
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APA006Hu01 Active Amphiregulin (AREG) Cell culture; Activity Assays.
RPA006Hu01 Recombinant Amphiregulin (AREG) Positive Control; Immunogen; SDS-PAGE; WB.
PAA006Hu01 Polyclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
MAA006Hu23 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
MAA006Hu25 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
MAA006Hu22 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC
MAA006Hu24 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC/IF
MAA006Hu26 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC
MAA006Hu21 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
MAA006Hu27 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
MAA006Hu29 Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC; IP.
LAA006Hu76 Biotin-Linked Monoclonal Antibody to Amphiregulin (AREG) WB; IHC; ICC.
SEA006Hu ELISA Kit for Amphiregulin (AREG) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA006Hu CLIA Kit for Amphiregulin (AREG) Chemiluminescent immunoassay for Antigen Detection.
LMA006Hu Multiplex Assay Kit for Amphiregulin (AREG) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
PSA006Hu01 Antibody Pair for Amphiregulin (AREG) ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSA006Hu01 ELISA Kit DIY Materials for Amphiregulin (AREG) Main materials for "Do It (ELISA Kit) Yourself".