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Recombinant Beclin 1 (BECN1)

ATG6; VPS30; Coiled-Coil,Myosin-Like BCL2 Interacting Protein; ATG6 Autophagy Related 6 Homolog

  • Product No.RPJ557Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationGolgi apparatus, trans-Golgi network membrane; Peripheral membrane protei
  • Predicted Molecular Mass35.2kDa
  • Accurate Molecular Mass42kDa(Analysis of differences refer to the manual)
  • Residues & TagsMet1~Thr273 (Accession # Q14457) with
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point4.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 178  US$ 446  US$ 892  US$ 2676  US$ 6690 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Rejuvenation Res. Can Enhanced Autophagy be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 are Increased in Healthy Centenarians Pubmed:25307612
J Cosmet Dermatol A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy pubmed:28342238
Tumor Biology The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models pubmed:28639900
19 Beclin1 circulating levels and accelerated ageing markers in COPD  DOI: 10.1183/1393003.congress-2017.PA1018
Cell Death & Disease Beclin1 circulating levels and accelerated aging markers in COPD Pubmed:29402890
Clinica Chimica Acta A novel combined score of biomarkers in sputum may be an indicator for lung cancer: A pilot study Doi: 10.1016/j.cca.2018.09.027
International Journal of Clinical and Experimental Pathology Serum concentration of autophagy-related protein 7 is correlated with non-alcoholic fatty liver disease in Chinese adults
EXPERIMENTAL AND THERAPEUTIC MEDICINE Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study 33936265
International Journal for Research in Applied Sciences and Biotechnology Inhibition of HepG-2 Cells (Liver Cancer Cell Line) Viability by 3-Hydroxypyridine-2-Carboxaldehyde N (4)-Methylthiosemicarbazone
BIOMARKERS OF AUTOPHAGY AND ANTIVIRAL ROLE OF PLACENTA FOR PREDICTING PRETERM DELIVERY IN PATIENTS WITH PRETERM DELIVERY?¡­
European Journal of Natural History IDENTIFICATION OF FACTORS CONNECTED WITH AUTOPHAGY ACTIVITY UNDER CONDITIONS OF PARTIAL NUTRITIONAL DEPRIVATION IN MEN
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPJ557Hu01 Recombinant Beclin 1 (BECN1) Positive Control; Immunogen; SDS-PAGE; WB.
PAJ557Hu01 Polyclonal Antibody to Beclin 1 (BECN1) WB; IHC
MAJ557Hu21 Monoclonal Antibody to Beclin 1 (BECN1) WB; IHC; ICC; IP.
MAJ557Hu22 Monoclonal Antibody to Beclin 1 (BECN1) WB; IHC; ICC; IP.
MAJ557Hu23 Monoclonal Antibody to Beclin 1 (BECN1) WB; IHC; ICC; IP.
MAJ557Hu24 Monoclonal Antibody to Beclin 1 (BECN1) WB; IHC; ICC; IP.
MAJ557Hu25 Monoclonal Antibody to Beclin 1 (BECN1) WB; IHC; ICC; IP.
SEJ557Hu ELISA Kit for Beclin 1 (BECN1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMJ557Hu Multiplex Assay Kit for Beclin 1 (BECN1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.