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Monoclonal Antibody to Beclin 1 (BECN1)

ATG6; VPS30; Coiled-Coil,Myosin-Like BCL2 Interacting Protein; ATG6 Autophagy Related 6 Homolog

SPECIFITY

The antibody is a mouse monoclonal antibody raised against BECN1. It has been selected for its ability to recognize BECN1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-5µg/mL
Immunohistochemistry: 5-50µg/mL
Immunocytochemistry: 5-50µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Rejuvenation Res. Can Enhanced Autophagy be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 are Increased in Healthy Centenarians Pubmed:25307612
J Cosmet Dermatol A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy pubmed:28342238
Tumor Biology The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models pubmed:28639900
19 Beclin1 circulating levels and accelerated ageing markers in COPD  DOI: 10.1183/1393003.congress-2017.PA1018
Cell Death & Disease Beclin1 circulating levels and accelerated aging markers in COPD Pubmed:29402890
Clinica Chimica Acta A novel combined score of biomarkers in sputum may be an indicator for lung cancer: A pilot study Doi: 10.1016/j.cca.2018.09.027
International Journal of Clinical and Experimental Pathology Serum concentration of autophagy-related protein 7 is correlated with non-alcoholic fatty liver disease in Chinese adults
EXPERIMENTAL AND THERAPEUTIC MEDICINE Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study 33936265
International Journal for Research in Applied Sciences and Biotechnology Inhibition of HepG-2 Cells (Liver Cancer Cell Line) Viability by 3-Hydroxypyridine-2-Carboxaldehyde N (4)-Methylthiosemicarbazone
BIOMARKERS OF AUTOPHAGY AND ANTIVIRAL ROLE OF PLACENTA FOR PREDICTING PRETERM DELIVERY IN PATIENTS WITH PRETERM DELIVERY?¡­
European Journal of Natural History IDENTIFICATION OF FACTORS CONNECTED WITH AUTOPHAGY ACTIVITY UNDER CONDITIONS OF PARTIAL NUTRITIONAL DEPRIVATION IN MEN
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
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