Recombinant Secreted Frizzled Related Protein 4 (SFRP4)
FRP-4; FRPHE; Frizzled protein, human endometrium
- Product No.RPF878Hu03
 - Organism SpeciesHomo sapiens (Human) Same name, Different species.
 - SourceProkaryotic expression
 - HostE.coli
 - Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
 - Subcellular LocationSecreted
 - Predicted Molecular Mass38.7kDa
 - Accurate Molecular Mass39kDa(Analysis of differences refer to the manual)
 - Residues & TagsAla22~Val346 with N-terminal His Tag
 - Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
 - Traits Freeze-dried powder
 - Purity> 97%
 - Isoelectric Point8.9
 - 
                        Applications
                        Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
 - UOM 10µg50µg 200µg 1mg 5mg
 - FOB
    
                                    US$ 168 
            
                
                        US$ 420 
                                        US$ 840 
                                        US$ 2520 
                                        US$ 6300 
                            
For more details, please contact local distributors! 
SEQUENCE
                                
                            USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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INCREMENT SERVICES
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                        Endotoxin Removal Kit
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                        BCA Protein Quantification Kit
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                        Protein Labeling Customized Service
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                        Molecular Mass Marker for Protein
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                        Recombinant Protein Customized Service
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                        Monoclonal Antibody Customized Service
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                        Polyclonal Antibody Customized Service
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                        Protein Activity Test Experiment Service
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                        Immunoprecipitation (IP) Experiment Service
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                        Buffer
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                        Endotoxin Removal Kit II
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                        Real Time PCR Experimental Service
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                        Spike RBD Protein (S-RBD)
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                        Protein G
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                        Protein A
                                     
| Magazine | Citations | 
| Endocrine Journal | Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance PubMed: 26041556 | 
| Horm Metab Res. | Secreted Frizzled-Related Protein 4 (SFRP4) is Elevated in Patients with Diabetes Mellitus Pubmed:26882051 | 
| Obesity (Silver Spring). | Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity pubmed:27768254 | 
| Obesity | Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans Pubmed:29427376 | 
| Novel marker for gestational diabetes patent:US20180059122A1 | |
| British Journal Of Nutrition | A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile Pubmed: 30375290 | 
| American Journal of Cancer Research | SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma Pubmed: 30906634 | 
| Diabetologia | Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic … Pubmed: 31011777 | 
| PLoS One | First trimester secreted Frizzled-Related Protein 4 and other adipokine serum concentrations in women developing gestational diabetes mellitus Pubmed: 33206702 | 
| Gastric Cancer | SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence 33277667 | 
| Diabetology | Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop … | 
        
                            
