Secreted Frizzled Related Protein 4 (SFRP4)
[Edit]FRP-4; FRPHE; Frizzled protein, human endometrium
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Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
Sequence analysis predicted that the 346-amino acid SFRP4 protein contains an N-terminal signal peptide, no transmembrane domain, and a hydrophilic C terminus. In situ hybridization analysis demonstrated exclusive expression in stromal and myometrial cells, particularly in endometrium and breast. Upregulated expression was detected in endometrial and breast carcinomas.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF878Mu01 | Recombinant Secreted Frizzled Related Protein 4 (SFRP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPF878Mu02 | Recombinant Secreted Frizzled Related Protein 4 (SFRP4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAF878Mu01 | Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) | WB; IHC; ICC; IP. |
| PAF878Mu02 | Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) | WB; IHC; ICC; IP. | |
| Assay Kits | SEF878Mu | ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF878Ra01 | Recombinant Secreted Frizzled Related Protein 4 (SFRP4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPF878Ra02 | Recombinant Secreted Frizzled Related Protein 4 (SFRP4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAF878Ra01 | Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) | WB; IHC; ICC; IP. |
| PAF878Ra02 | Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) | WB; IHC; ICC; IP. | |
| LAF878Ra71 | Biotin-Linked Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) | WB; IHC; ICC. | |
| Assay Kits | SEF878Ra | ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "Expression of secreted frizzled-related protein 4 (SFRP4) in primary serous ovarian tumours."Eur. J. Gynaecol. Oncol. 30:133-141(2009) [PubMed] [Europe PMC] [Abstract]