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Recombinant Amyloid Precursor Protein (APP)

AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein

  • Product No.RPB020Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass60kDa
  • Accurate Molecular Mass60kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu18~Val286 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point3.88
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 180  US$ 450  US$ 900  US$ 2700  US$ 6750 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neurochemistry International Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway ScienceDirect: S0197018611001641
Neuroscience Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein Pubmed: 23707801
OncoImmunology PROOF COVER SHEET
台湾农业研究 (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
Metab Brain Dis Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928
Exp Gerontol The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and … Pubmed:35217193
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB020Ra01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
PAB020Ra01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
MAB020Ra21 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
WEB020Ra Wide-range ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB020Ra ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB020Ra Multiplex Assay Kit for Amyloid Precursor Protein (APP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.