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Amyloid Precursor Protein (APP)

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AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein

Amyloid Precursor Protein (APP)
CCC B020
HGNC 620
MGI 88059
PubMed 12824062
RGD 2139
UniProt P05067
Wiki APP

Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation and neural plasticity. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.Several alternative splicing isoforms of APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Hu01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Hu02 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Hu03 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB020Hu01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
MAB020Hu22 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
MAB020Hu23 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
PAB020Hu02 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
PAB020Hu03 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
Assay Kits SEB020Hu ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB020Hu CLIA Kit for Amyloid Precursor Protein (APP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Mu01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Mu02 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB020Mu01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
PAB020Mu02 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
LAB020Mu71 Biotin-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC.
LAB020Mu81 FITC-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IF.
Assay Kits SEB020Mu ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB020Ra01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB020Ra01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
MAB020Ra21 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
Assay Kits SEB020Ra ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
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