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Monoclonal Antibody to Amyloid Precursor Protein (APP)

AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein

  • Product No.MAB020Ra21
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 115  US$ 267  US$ 382  US$ 955  US$ 3820 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against APP. It has been selected for its ability to recognize APP in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neurochemistry International Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway ScienceDirect: S0197018611001641
Neuroscience Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein Pubmed: 23707801
OncoImmunology PROOF COVER SHEET
台湾农业研究 (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
Metab Brain Dis Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928
Exp Gerontol The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and … Pubmed:35217193
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB020Ra01 Recombinant Amyloid Precursor Protein (APP) Positive Control; Immunogen; SDS-PAGE; WB.
PAB020Ra01 Polyclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
MAB020Ra21 Monoclonal Antibody to Amyloid Precursor Protein (APP) WB; IHC; ICC; IP.
WEB020Ra Wide-range ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
SEB020Ra ELISA Kit for Amyloid Precursor Protein (APP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB020Ra Multiplex Assay Kit for Amyloid Precursor Protein (APP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.