Eukaryotic Syndecan 1 (SDC1)
CD138; SDC; SYND1; Syndecan Proteoglycan 1
- Product No.EPB966Hu61
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceEukaryotic expression
- Host293F Cell
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane, Secreted
- Predicted Molecular Mass25.4kDa
- Accurate Molecular Mass60kDa(Analysis of differences refer to the manual)
- Residues & TagsGln23~Leu253 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder
- Purity> 90%
- Isoelectric Point4.3
-
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 248
For more details, please contact local distributors! US$ 620 US$ 1240 US$ 3720 US$ 9300
SEQUENCE
![](/upload/product/pictures/EPB966Hu61-201805181018465334.jpg)
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Electrophoretic Mobility Shift Assay (EMSA) Experiment Service
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Buffer
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Lentivirus Packaging Experiment Service
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Adenovirus Packaging Experiment Service
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
Magazine | Citations |
Molecular and Cellular Biochemistry | Increased level of soluble syndecan-1 in serum correlates with myocardial expression in a rat model of myocardial infarction SpringerLink: a201w3l18k257462 |
Inflammation | Sdc1 Overexpression Inhibits the p38 MAPK Pathway and Lessens Fibrotic Ventricular Remodeling in MI Rats Springer: Source |
Atherosclerosis. | Damage of the endothelial glycocalyx in chronic kidney disease Pubmed:24727235 |
Journal of Trauma and Acute Care Surgery | Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury Pubmed:25058256 |
Shock | Impairment of the Endothelial Glycocalyx in Cardiogenic Shock and its Prognostic Relevance Pubmed:25692257 |
Mediators Inflamm | Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding PubMed: 26199464 |
Transplantation | Platelet-Derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury. PubMed: 26371596 |
Clinical and Experimental Nephrology | Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute kidney injury pubmed:27405618 |
Biomarkers in Medicine | Endothelial glycocalyx layer shedding following lung resection pubmed:27643669 |
Danish National RESEARCH DATABASE | Resuscitation with Pooled and Pathogen-Reduced Plasma Attenuates the Increase in Brain Water Content following Traumatic Brain Injury and Hemorrhagic Shock in Rats 10.1089 |
Journal of Neurotrauma | Resuscitation with pooled and pathogen-reduced plasma attenuates the increase in brain water content following traumatic brain injury and hemorrhagic shock in rats the rat. doi/10.1089/neu.2016.4574 |
British Journal of Anaesthesia | Volume kinetics of Ringer's lactate solution in acute inflammatory disease 10.1016:j.bja.2018.04.023 |
Arteriosclerosis, Thrombosis, and Vascular Biology | MPO (myeloperoxidase) reduces endothelial glycocalyx thickness dependent on its cationic charge Pubmed:29903730 |
Shock | Plasma resuscitation improved survival in a cecal ligation and puncture rat model of sepsis Pubmed:28591008 |
Shock | Experimental models of endotheliopathy: impact of shock severity Pubmed:28697004 |
Journal of Trauma and Acute Care Surgery | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat Pubmed:28930945 |
The Endothelial Glycocalyx in the Peritoneal Microcirculation of Rats with Chronic Kidney Failure Exposed to Dialysis Solutions 173015_06.pdf | |
Journal of Surgical Research | Plasma ameliorates endothelial dysfunction in burn injury Doi: 10.1016/j.jss.2018.08.027 |
Journal of Anesthesia | Dexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model Pubmed: 30374889 |
Anaesthesia | Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass Pubmed: 30687934 |
Journal of Cardiothoracic and Vascular Anesthesial | Microvascular alterations during cardiac surgery using a heparin or phosphorylcholine coated circuit Pubmed: 31787433 |
Hepatobiliary & Pancreatic Diseases International | Increased syndecan-1 and glypican-3 predict poor perinatal outcome and treatment resistance in intrahepatic cholestasis: Syndecan-1, glypican-3 and ICP Pubmed: 31919038 |
Heparin Binding Protein and Endothelial Glycocalyx Markers in Severe COVID-19–A Prospective Observational Cohort Study | |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis 33375342 |
Microvasc Res | Effect of liraglutide on microcirculation in rat model with absolute insulin deficiency 34119534 |
J Gerontol A Biol Sci Med Sci | The effect of pre-operative methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery: a randomized, double-blind, placebo … 34423832 |
Shock | Inhalation of 2% hydrogen improves survival rate and attenuates shedding of vascular endothelial glycocalyx in rats with heat stroke 34524269 |
Exp Anim | Dexmedetomidine suppresses serum syndecan-1 elevation and improves survival in a rat hemorrhagic shock model Pubmed:35110424 |
Journal of Emergency Medicine | Resuscitation of hemorrhagic shock using normal saline does not damage the glycocalyx in the immediate resuscitation phase |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
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EPB966Hu61 | Eukaryotic Syndecan 1 (SDC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB966Hu02 | Recombinant Syndecan 1 (SDC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB966Hu03 | Recombinant Syndecan 1 (SDC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB966Hu01 | Polyclonal Antibody to Syndecan 1 (SDC1) | WB; IHC |
FAB966Hu01 | Anti-Syndecan 1 (SDC1) Polyclonal Antibody | Flow cytometry. |
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MAB966Hu23 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
MAB966Hu22 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
MAB966Hu24 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
MAB966Hu25 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
RAB966Hu21 | Recombinant Antibody to Syndecan 1 (SDC1) | WB; IF; ICC; IHC; IP; FCM. |
MAB966Hu27 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
MAB966Hu29 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
SEB966Hu | ELISA Kit for Syndecan 1 (SDC1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
HEB966Hu | High Sensitive ELISA Kit for Syndecan 1 (SDC1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB966Hu | Multiplex Assay Kit for Syndecan 1 (SDC1) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |
KSB966Hu01 | ELISA Kit DIY Materials for Syndecan 1 (SDC1) | Main materials for "Do It (ELISA Kit) Yourself". |