Syndecan 1 (SDC1)

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CD138; SDC; SYND1; Syndecan Proteoglycan 1

Syndecan 1 (SDC1)

Syndecan 1 is  a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB966Hu01 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
EPB966Hu61 Eukaryotic Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Hu02 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Hu03 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
EPB966Hu62 Eukaryotic Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB966Hu01 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC
MAB966Hu22 Monoclonal Antibody to Syndecan 1 (SDC1) WB
MAB966Hu21 Monoclonal Antibody to Syndecan 1 (SDC1) WB; IHC
MAB966Hu23 Monoclonal Antibody to Syndecan 1 (SDC1) WB
MAB966Hu24 Monoclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
MAB966Hu25 Monoclonal Antibody to Syndecan 1 (SDC1) WB
MAB966Hu27 Monoclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
MAB966Hu29 Monoclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
Assay Kits SEB966Hu ELISA Kit for Syndecan 1 (SDC1) Enzyme-linked immunosorbent assay for Antigen Detection.
HEB966Hu High Sensitive ELISA Kit for Syndecan 1 (SDC1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB966Mu01 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Mu02 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
EPB966Mu62 Eukaryotic Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB966Mu01 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
PAB966Mu02 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
Assay Kits SEB966Mu ELISA Kit for Syndecan 1 (SDC1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB966Ra01 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Ra02 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB966Ra01 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
MAB966Ra21 Monoclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
LAB966Ra81 FITC-Linked Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IF.
PAB966Ra02 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
Assay Kits SEB966Ra ELISA Kit for Syndecan 1 (SDC1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB966Po01 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Po02 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB966Po03 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB966Po01 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
PAB966Po02 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
PAB966Po03 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
Assay Kits SEB966Po ELISA Kit for Syndecan 1 (SDC1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB966Bo01 Recombinant Syndecan 1 (SDC1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB966Bo01 Polyclonal Antibody to Syndecan 1 (SDC1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Syndecan 1 (SDC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syndecan 1 (SDC1) ELISA Kit Customized Service Offer
  1. "Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts."J. Biol. Chem. 267:1116-1122(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans."J. Biol. Chem. 265:6884-6889(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Shift of syndecan-1 expression from epithelial to stromal cells during progression of solid tumours."Eur. J. Cancer 40:1373-1382(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The mapping and visual ordering of the human syndecan-1 and N-myc genes near the telomeric region of chromosome 2p."Hum. Genet. 99:295-297(1997) [PubMed] [Europe PMC] [Abstract]
  7. "Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation."J. Biol. Chem. 272:14713-14720(1997) [PubMed] [Europe PMC] [Abstract]
  8. "Adhesion signaling by a novel mitotic substrate of src kinases."Oncogene 24:5333-5343(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics."Structure 21:342-354(2013) [PubMed] [Europe PMC] [Abstract]