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Recombinant Noggin (NOG)

SYM1; SYNS1; Synostoses(Multiple)Syndrome 1; Symphalangism 1(Proximal)

  • Product No.RPC130Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass24.3kDa
  • Accurate Molecular Mass24kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln28~Cys232 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point9.0
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 159  US$ 398  US$ 796  US$ 2388  US$ 5970 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Arthritis Rheumatol Imbalance between BMP2 and Noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis PubMed: 26413886
Arthritis Rheumatol.  Imbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal Osteogenic Differentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis Pubmed:26413886
Clin Exp Pharmacol Physiol. Oxygen-glucose deprivation preconditioning protects neurons against oxygen-glucose deprivation/reperfusion induced injury via bone morphogenetic protein-7 mediated ERK, p38 and Smad signalling pathways. Pubmed:26385023
European cells & materials The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. pubmed:28266688
Arthritis & Rheumatology mbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal OsteogenicDifferentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis. pubmed:26413886
Biotechnology and Applied Biochemistry The BMP antagonist Noggin is produced by osteoblasts in response to the presence of prostate cancer cells. pubmed:28981962
Heliyon Efficient in vitro delivery of Noggin siRNA enhances osteoblastogenesis pubmed:29167826
Journal of Cellular Biochemistry Low‐intensity pulsed ultrasound promotes bone morphogenic protein 9‐induced osteogenesis and suppresses inhibitory effects of inflammatory cytokines on cellular … Pubmed: 31006911
Aging Male Effect of tadalafil on penile nitric oxide synthase and corporal smooth muscle in rats under dutasteride treatment Pubmed: 32160825
J Reconstr Microsurg Effect of Simvastatin Use in Free Tissue Transfer: An Experimental Study in a Rat Epigastric Free Flap Model Pubmed: 31995818
Biochem Biophys Rep Slow diffusion on the monolayer culture enhances auto/paracrine effects of Noggin in differentiation of human iPS cells induced by BMP Pubmed:35005256
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APC130Hu01 Active Noggin (NOG) Cell culture; Activity Assays.
RPC130Hu01 Recombinant Noggin (NOG) Positive Control; Immunogen; SDS-PAGE; WB.
RPC130Hu02 Recombinant Noggin (NOG) Positive Control; Immunogen; SDS-PAGE; WB.
EPC130Hu61 Eukaryotic Noggin (NOG) Positive Control; Immunogen; SDS-PAGE; WB.
PAC130Hu01 Polyclonal Antibody to Noggin (NOG) WB; IHC; ICC; IP.
PAC130Hu02 Polyclonal Antibody to Noggin (NOG) WB; IHC; ICC; IP.
LAC130Hu71 Biotin-Linked Polyclonal Antibody to Noggin (NOG) WB; IHC; ICC.
LAC130Hu81 FITC-Linked Polyclonal Antibody to Noggin (NOG) WB; IHC; ICC; IF.
MAC130Hu21 Monoclonal Antibody to Noggin (NOG) WB; IHC; ICC; IP.
MAC130Hu22 Monoclonal Antibody to Noggin (NOG) WB,IHC
MAC130Hu24 Monoclonal Antibody to Noggin (NOG) WB,IHC
MAC130Hu26 Monoclonal Antibody to Noggin (NOG) WB,IHC
LAC130Hu76 Biotin-Linked Monoclonal Antibody to Noggin (NOG) WB; IHC; ICC.
SEC130Hu ELISA Kit for Noggin (NOG) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC130Hu Multiplex Assay Kit for Noggin (NOG) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
PSC130Hu01 Antibody Pair for Noggin (NOG) ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSC130Hu01 ELISA Kit DIY Materials for Noggin (NOG) Main materials for "Do It (ELISA Kit) Yourself".