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Recombinant Complement Component 5 (C5)

CPAMD4; C5a anaphylatoxin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

  • Product No.RPB969Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass55.2kDa
  • Accurate Molecular Mass55kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer1055~Asn1513 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 184  US$ 460  US$ 920  US$ 2760  US$ 6900 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Journal of Clinical Immunology Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511
Journal of Neuroimmunology Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358
Cancer Letters Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression pubmed:29031586
Proteomics Clinical Applications iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism Pubmed:29274201
American journal of physiology. Endocrinology and metabolism Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency Pubmed: 31084499
Proteomics Clinical Applications Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828
Aging C5aR deficiency attenuates the breast cancer development via the p38/p21 axis Pubmed: 32669478
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB969Hu01 Recombinant Complement Component 5 (C5) Positive Control; Immunogen; SDS-PAGE; WB.
APB969Hu02 Active Complement Component 5 (C5) Cell culture; Activity Assays.
RPB969Hu02 Recombinant Complement Component 5 (C5) Positive Control; Immunogen; SDS-PAGE; WB.
PAB969Hu01 Polyclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC; IP.
PAB969Hu02 Polyclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC; IP.
LAB969Hu71 Biotin-Linked Polyclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC.
MAB969Hu22 Monoclonal Antibody to Complement Component 5 (C5) WB; IHC; ICC; IP.
SEB969Hu ELISA Kit for Complement Component 5 (C5) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB969Hu Multiplex Assay Kit for Complement Component 5 (C5) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.