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Recombinant NADPH Oxidase 4 (NOX4)

KOX; KOX-1; RENOX; Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4

  • Product No.RPB924Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Nucleus
  • Predicted Molecular Mass21.2kDa
  • Accurate Molecular Mass21kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsp220~Asp392 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 168  US$ 420  US$ 840  US$ 2520  US$ 6300 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Chem Biol Interact Apocynin protects against ethanol-induced gastric ulcer in rats by attenuating the upregulation of NADPH oxidases 1 and 4 PubMed: 26522475
Prostate Oxidative stress promotes benign prostatic hyperplasia PubMed: 26417670
PLoS One. Effects of Single and Combined Losartan and Tempol Treatments on Oxidative Stress, Kidney Structure and Function in Spontaneously Hypertensive Rats with Early Course of Proteinuric Nephropathy. pubmed:27560781
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4. pubmed:28431936
Experimental and Therapeutic Medicine Chronic restraint stress induces esophageal fibrosis with enhanced oxidative stress in a murine model
PLoS Biol NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype Pubmed: 33170835
Free Radic Biol Med Biphasic changes in TGF-β1 signaling drive NSAID-induced multi-organ damage Pubmed: 32750407
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB924Hu02 Recombinant NADPH Oxidase 4 (NOX4) Positive Control; Immunogen; SDS-PAGE; WB.
RPB924Hu01 Recombinant NADPH Oxidase 4 (NOX4) Positive Control; Immunogen; SDS-PAGE; WB.
PAB924Hu01 Polyclonal Antibody to NADPH Oxidase 4 (NOX4) WB; IHC
PAB924Hu02 Polyclonal Antibody to NADPH Oxidase 4 (NOX4) WB; IHC; ICC; IP.
LAB924Hu71 Biotin-Linked Polyclonal Antibody to NADPH Oxidase 4 (NOX4) WB; IHC; ICC.
MAB924Hu22 Monoclonal Antibody to NADPH Oxidase 4 (NOX4) WB; IHC; ICC; IP.
SEB924Hu ELISA Kit for NADPH Oxidase 4 (NOX4) Enzyme-linked immunosorbent assay for Antigen Detection.
MEB924Hu Mini Samples ELISA Kit for NADPH Oxidase 4 (NOX4) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB924Hu Multiplex Assay Kit for NADPH Oxidase 4 (NOX4) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.