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Recombinant Mannose Associated Serine Protease 1 (MASP1)

CRARF; PRSS5; Mannan-Binding Lectin Serine Peptidase 1; Ra-reactive factor serine protease p100; Complement-activating component of Ra-reactive factor; Serine protease 5

  • Product No.RPB895Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass52.7kDa
  • Accurate Molecular Mass53kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis20~Ala447 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point5.2
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 160  US$ 400  US$ 800  US$ 2400  US$ 6000 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pathology Increased Circulating Plasma Mannose Binding Lectin Associated Serine Protease (Masp) As A Result of Enu-Induced Mutation in Masp-1 Lww: Source
The Journal fo Biological Chemistry Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype Pubmed:24550392
the journal of immunology The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema PubMed: 26371246
J Neuroinflammation.  Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis PMC5234106
Frontiers in Immunology AmpliSeq screening of genes encoding the C-type lectin receptors and their signaling components reveals a common variant in MASP1 associated with … Pubmed:29515573
Journal of Proteomics Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approach Pubmed: 30605725
Kidney International Reports Clinical value of complement activation biomarkers in overt diabetic nephropathy
Kidney International Reports Comparison of Complement Pathway Activation in Autoimmune Glomerulonephritis Pubmed:35571000
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB895Hu01 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB895Hu01 Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB,IHC
MAB895Hu22 Monoclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB; IHC; ICC; IP.
SEB895Hu ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB895Hu Multiplex Assay Kit for Mannose Associated Serine Protease 1 (MASP1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.