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Mannose Associated Serine Protease 1 (MASP1)

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CRARF; PRSS5; Mannan-Binding Lectin Serine Peptidase 1; Ra-reactive factor serine protease p100; Complement-activating component of Ra-reactive factor; Serine protease 5

Mannose Associated Serine Protease 1 (MASP1)
CCC B895
HGNC 6901
MGI 88492
PubMed 9777417
RGD 620213
UniProt P48740
Wiki MASP1

  • Mannose-associated serine protease 1 (MASP1) is involved in the lectin pathway of the complement system and is responsible for cleaving C4 and C2 to form C4b2a, a C3-convertase.Mannose-binding lectin (MBL) is a serum component which participates in innate immunity by activating complement via a novel pathway. Human MBL forms complexes with two types of serine proteases termed MASP (MBL-associated serine protease).

  • These two proteases, MASP1 and MASP2, are structurally similar to one another as well as to C1r and C1s. Together, MASP, C1r and C1s constitute a novel serine protease family. It is likely that human MASP1 is able to activate C3, while human MASP2 cleaves C4, although further functional studies are required to confirm this.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB895Hu01 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB895Hu01 Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB,IHC
MAB895Hu22 Monoclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB; IHC; ICC; IP.
Assay Kits SEB895Hu ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB895Mu01 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB895Mu02 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB895Mu01 Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB,IHC
PAB895Mu02 Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) WB; IHC; ICC; IP.
Assay Kits SEB895Mu ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mannose Associated Serine Protease 1 (MASP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mannose Associated Serine Protease 1 (MASP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) ELISA Kit Customized Service Offer
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  26. "Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome." Nat. Genet. 43:197-203(2011) [PubMed] [Europe PMC] [Abstract]