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Recombinant Permeability Glycoprotein (Pgp)

CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin Sensitivity

  • Product No.RPB690Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Secreted
  • Predicted Molecular Mass33.8kDa
  • Accurate Molecular Mass34kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla999~Ser1277 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point9.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 136  US$ 340  US$ 680  US$ 2040  US$ 5100 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International Forum of Allergy & Rhinology P-glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polyps Onlinelibrary: alr.21316
International Forum of Allergy & Rhinology P‐glycoprotein regulates Staphylococcus aureus enterotoxin B–stimulated interleukin‐5 and thymic stromal lymphopoietin secretion in organotypic mucosal explants PubMed: 26625351
American Journal of Rhinology & Allergy Intact soluble P-glycoprotein is secreted by sinonasal epithelial cells. pubmed:27456593
The Laryngoscope Secreted P-glycoprotein is a noninvasive biomarker of chronic rhinosinusitis pubmed:27577924
Materials Science and Engineering: C Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia
Molecular Cancer Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance Pubmed: 31830995
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB690Ra01 Recombinant Permeability Glycoprotein (Pgp) Positive Control; Immunogen; SDS-PAGE; WB.
PAB690Ra01 Polyclonal Antibody to Permeability Glycoprotein (Pgp) WB; IHC; ICC; IP.
SEB690Ra ELISA Kit for Permeability Glycoprotein (Pgp) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB690Ra Multiplex Assay Kit for Permeability Glycoprotein (Pgp) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.