Recombinant Caspase 1 (CASP1)
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
- Product No.RPB592Hu04
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane, Cytoplasm
- Predicted Molecular Mass62.0kDa
- Accurate Molecular Mass60kDa(Analysis of differences refer to the manual)
- Residues & TagsAsn120~His404 with N-terminal His and GST Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 95%
- Isoelectric Point6.3
-
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 142
For more details, please contact local distributors! US$ 355 US$ 710 US$ 2130 US$ 5325
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
- Endotoxin Removal Kit
- BCA Protein Quantification Kit
- Protein Labeling Customized Service
- Molecular Mass Marker for Protein
- Recombinant Protein Customized Service
- Monoclonal Antibody Customized Service
- Polyclonal Antibody Customized Service
- Protein Activity Test Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Buffer
- Endotoxin Removal Kit II
- Real Time PCR Experimental Service
- Spike RBD Protein (S-RBD)
- Protein G
- Protein A
Magazine | Citations |
PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434 |
Fertil Steril | Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” PubMed: 26474737 |
PLoS One | Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. pubmed:28704412 |
Journal of Virology | NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination Pubmed:29386291 |
Journal of Translational Medicine | Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? Pubmed:29665864 |
Reproductive Sciences | A role for the inflammasome in spontaneous labor at term Pubmed:27852921 |
Journal of Virology | CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES Pubmed: 29386291 |
ACTA Otorhinolaryngologica Italica | NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media Pubmed: 30676848 |
American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women Pubmed: 31148259 |
Taiwanese Journal of Obstetrics & Gynecology | Serum Caspase-1 levels in women with polycystic ovary syndrome Pubmed: 32127139 |
Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients |
ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES | |
Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER |
LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation 34560082 |
Biol Reprod | The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice 34632484 |
J Mol Neurosci | TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury Pubmed:35041191 |
Viruses | Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion Pubmed:35062292 |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
RPB592Hu02 | Recombinant Caspase 1 (CASP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB592Hu01 | Recombinant Caspase 1 (CASP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB592Hu03 | Recombinant Caspase 1 (CASP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB592Hu04 | Recombinant Caspase 1 (CASP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB592Hu01 | Polyclonal Antibody to Caspase 1 (CASP1) | WB; IHC; ICC; IP. |
PAB592Hu04 | Polyclonal Antibody to Caspase 1 (CASP1) | WB; IHC; ICC; IP. |
PAB592Hu02 | Polyclonal Antibody to Caspase 1 (CASP1) | WB,IHC,ICC/IF |
LAB592Hu71 | Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1) | WB; IHC; ICC. |
LAB592Hu81 | FITC-Linked Polyclonal Antibody to Caspase 1 (CASP1) | WB; IHC; ICC; IF. |
MAB592Hu22 | Monoclonal Antibody to Caspase 1 (CASP1) | WB; IHC; ICC; IP. |
SEB592Hu | ELISA Kit for Caspase 1 (CASP1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB592Hu | Multiplex Assay Kit for Caspase 1 (CASP1) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |
KSB592Hu01 | ELISA Kit DIY Materials for Caspase 1 (CASP1) | Main materials for "Do It (ELISA Kit) Yourself". |