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Caspase 1 (CASP1)

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ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase

Caspase 1 (CASP1)
CCC B592
HGNC 1499
MGI 96544
PubMed 19950280
RGD 2274
UniProt P29466
Wiki Caspase_1

Caspase 1 is an enzyme that proteolytically cleaves other proteins, such as the precursor forms of the inflammatory cytokines interleukin 1-beta and interleukin 18, into active mature peptides. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue.

Caspase 1 is produced as a zymogen that is cleaved into 20 kDa (p20) and 10 kDa (p10) subunits that become part of the active enzyme. Active caspase 1 contains two heterodimers of p20 and p10. It interacts with another CARD domain containing protein called PYCARD (or ASC) and is involved in inflammasome formation and activation of inflammatory processes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB592Hu01 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB592Hu02 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB592Hu03 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB592Hu04 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB592Hu01 Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
MAB592Hu22 Monoclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
PAB592Hu02 Polyclonal Antibody to Caspase 1 (CASP1) WB,IHC,ICC/IF
LAB592Hu71 Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC.
LAB592Hu81 FITC-Linked Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IF.
PAB592Hu04 Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
Assay Kits SEB592Hu ELISA Kit for Caspase 1 (CASP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB592Mu01 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB592Mu02 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB592Mu01 Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
LAB592Mu71 Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC.
PAB592Mu02 Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
Assay Kits SEB592Mu ELISA Kit for Caspase 1 (CASP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB592Ra01 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
APB592Ra01 Active Caspase 1 (CASP1) Cell culture; Activity Assays.
Antibodies PAB592Ra01 Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
LAB592Ra71 Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC.
MAB592Ra21 Monoclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC; IP.
Assay Kits SEB592Ra ELISA Kit for Caspase 1 (CASP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB592Po01 Recombinant Caspase 1 (CASP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB592Po01 Polyclonal Antibody to Caspase 1 (CASP1) WB,IHC,ICC/IF
LAB592Po71 Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Caspase 1 (CASP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Caspase 1 (CASP1) ELISA Kit Customized Service Offer
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