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Recombinant Semaphorin 4D (SEMA4D)

CD100; A8; BB18; GR3; M-Sema G; M-Sema-G; SEMAJ; Coll-4; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 4D

  • Product No.RPB430Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass16.2kDa
  • Accurate Molecular Mass18kDa(Analysis of differences refer to the manual)
  • Residues & TagsPhe502~Phe636 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point8.8
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 164  US$ 410  US$ 820  US$ 2460  US$ 6150 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Expert Opin Ther Targets. Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment Pubmed:25395071
Obesity (Silver Spring). Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index. pubmed:28296344
Clinical Lymphoma, Myeloma & Leukemia A Revised Staging System for Waldenström's Macroglobulinemia 10.1016/j.clml.2017.07.146
Clinical Lymphoma, Myeloma & Leukemia Extramedullary Multiple Myeloma: Clinical Features and Prognosis in Argentina 10.1016/j.clml.2017.07.144
Blood Cancer Journal Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma Pubmed:29748532
Analytical Biochemistry A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma Pubmed: 30879960
Journal of Allergy and Clinical Immunology-In Practice Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis Pubmed: 32035658
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB430Hu01 Recombinant Semaphorin 4D (SEMA4D) Positive Control; Immunogen; SDS-PAGE; WB.
PAB430Hu01 Polyclonal Antibody to Semaphorin 4D (SEMA4D) WB; IHC; ICC; IP.
MAB430Hu22 Monoclonal Antibody to Semaphorin 4D (SEMA4D) WB; IHC; ICC; IP.
SEB430Hu ELISA Kit for Semaphorin 4D (SEMA4D) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB430Hu Multiplex Assay Kit for Semaphorin 4D (SEMA4D) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.