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Recombinant Runt Related Transcription Factor 2 (RUNX2)

AML3; CBFA1; CCD1; OSF2; PEBP2A; Acute myeloid leukemia 3 ; Core-binding factor alpha-1; Osteoblast-specific transcription factor 2; Polyomavirus enhancer-binding protein 2 A

  • Product No.RPB011Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus
  • Predicted Molecular Mass25.3kDa
  • Accurate Molecular Mass26kDa(Analysis of differences refer to the manual)
  • Residues & TagsTyr299~Tyr521 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 186  US$ 466  US$ 932  US$ 2796  US$ 6990 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International Journal of Cardiology Valvular osteoclasts in calcification and aortic valve stenosis severity PubMed: 23452891
BioMed Research International Serum Heme Oxygenase-1 and BMP-7 Are Potential Biomarkers for Bone Metabolism in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Pubmed:27314037
Journal of Biomedical Materials Research New method for the fabrication of highly osteoconductive β‐1, 3‐glucan/HA scaffold for bone tissue engineering: Structural, mechanical, and biological … doi:10.1002
International Journal of Pharmaceutical Sciences MicroRNA-320a protects against osteoarthritis cartilage degeneration by regulating the expressions of BMI-1 and RUNX2 in chondrocytes 10.1691:ph.2017.6890
Dental Materials Journal Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells. pubmed:28228629
Biomedicine & pharmacotherapy Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation. pubmed:28742995
Biochemical and biophysical research communications Cereblon (CRBN) deletion reverses streptozotocin induced diabetic osteoporosis in mice Pubmed:29353038
Journal of Infection and Chemotherapy Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity Pubmed:29753615
medical science monitor Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132 … Pubmed: 30923307
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES Febuxostat attenuates vascular calcification induced by vitamin D3 plus nicotine in rats Pubmed: 33010420
Molecular Medicine Reports Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism Pubmed: 33000198
Effect of Corticopuncture (CP), Photobiomodulation (PBM) and the Combined Method on the Rate of Tooth Movement and Root Resorption: A Molecular, Histological …
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB011Hu01 Recombinant Runt Related Transcription Factor 2 (RUNX2) Positive Control; Immunogen; SDS-PAGE; WB.
PAB011Hu01 Polyclonal Antibody to Runt Related Transcription Factor 2 (RUNX2) WB; IHC; ICC; IP.
MAB011Hu22 Monoclonal Antibody to Runt Related Transcription Factor 2 (RUNX2) WB; IHC; ICC; IP.
SEB011Hu ELISA Kit for Runt Related Transcription Factor 2 (RUNX2) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB011Hu Multiplex Assay Kit for Runt Related Transcription Factor 2 (RUNX2) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.