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Recombinant Cyclophilin A (CYPA)

PPIA; CyP-A; CYPH; Peptidylprolyl Isomerase A; Peptidyl-Prolyl Isomerase A; Peptidyl-prolyl cis-trans isomerase A; Cyclosporin A-binding protein

  • Product No.RPA979Mu02
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular Locationn/a
  • Predicted Molecular Massn/a
  • Accurate Molecular Massn/a(Analysis of differences refer to the manual)
  • Residues & TagsN-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Pointn/a
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • Downloadn/a
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 140  US$ 350  US$ 700  US$ 2100  US$ 5250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Atherosclerosis EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation PubMed: 19758589
Biomarkers Cyclophilin-A: a novel biomarker for untreated male essential hypertension Pubmed: 24164594
Cardiovascular Diabetology Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease Pubmed:24502618
International Journal of Biological Sciences Decrease in Plasma Cyclophilin A Concentration at 1 Month after Myocardial Infarction Predicts Better Left Ventricular Performance and Synchronicity at 6 Months: A Pilot Study in Patients with ST Elevation Myocardial Infarction Pubmed:25552928
Medicine Cyclophilin A in Ruptured Intracranial Aneurysm PubMed: 26426668
Mol Cell Biochem PPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease PubMed: 26702934
Medicine (Baltimore) Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus PubMed: 26496315
International Journal of Cardiology Cyclophilin A modulates bone marrow-derived CD117(+) cells and enhances ischemia-induced angiogenesisvia the SDF-1/CXCR4 axis. Pubmed:27057951
Clinica Chimica Acta Novel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor pubmed:27823952
Cardiovascular Diabetology Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. pubmed:27809851
Clinical Science Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity Pubmed:29382697
Journal of Molecular Histology Cyclophilin a increases CD68 cell infiltration in rat experimental periodontitis Pubmed:29318411
Free Radical Research Cyclophilin A and CD147 associate with progression of diabetic nephropathy Pubmed: 30572748
The Kaohsiung Journal of Medical Sciences Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction Pubmed: 31670477
Cells. Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients Pubmed: 31936351
JAMA Neurology APPENDIX A: Relationship between cyclophilin A levels and matrix metalloproteinase-9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers … Pubmed: 24030206
Menoufia Medical Journal Urinary podocalyxin and cyclophilin A: markers for early detection of type 2 diabetic nephropathy
Toxins Evaluation of the Therapeutic Effects of Protocatechuic Aldehyde in Diabetic Nephropathy 34437430
Cell Death & Disease Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death Pubmed:35732625
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA979Mu01 Recombinant Cyclophilin A (CYPA) Positive Control; Immunogen; SDS-PAGE; WB.
RPA979Mu02 Recombinant Cyclophilin A (CYPA) Positive Control; Immunogen; SDS-PAGE; WB.
PAA979Mu02 Polyclonal Antibody to Cyclophilin A (CYPA) WB; IHC; ICC; IP.
PAA979Mu01 Polyclonal Antibody to Cyclophilin A (CYPA) WB; IHC; ICC; IP.
FAA979Mu01 Anti-Cyclophilin A (CYPA) Polyclonal Antibody Flow cytometry.
LAA979Mu81 FITC-Linked Polyclonal Antibody to Cyclophilin A (CYPA) WB; IHC; ICC; IF.
LAA979Mu71 Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) WB; IHC; ICC.
MAA979Mu21 Monoclonal Antibody to Cyclophilin A (CYPA) WB; IHC; ICC; IP.
MAA979Mu22 Monoclonal Antibody to Cyclophilin A (CYPA) WB; IHC
HEA979Mu High Sensitive ELISA Kit for Cyclophilin A (CYPA) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA979Mu ELISA Kit for Cyclophilin A (CYPA) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA979Mu Multiplex Assay Kit for Cyclophilin A (CYPA) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
PSA979Mu01 Antibody Pair for Cyclophilin A (CYPA) ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSA979Mu01 ELISA Kit DIY Materials for Cyclophilin A (CYPA) Main materials for "Do It (ELISA Kit) Yourself".