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Recombinant Collagen Type I Alpha 1 (COL1a1)

COL-1A1; COL1-A1; COL1A-1; OI4; Collagen Alpha-1(I)chain

  • Product No.RPA350Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Predicted Molecular Mass26.4kDa
  • Accurate Molecular Mass28kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla1218~Ile1440 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 156  US$ 390  US$ 780  US$ 2340  US$ 5850 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology Simvastatin-loaded porous implant surfaces stimulate preosteoblasts differentiation: an in vitro study ScienceDirect: S1079210410004919
Journal of Biomedical Materials Osteoblast response to puerarin-loaded porous titanium surfaces: An in vitro study Wiley: source
European Archives of Oto-Rhino-Laryngology Age effects on extracellular matrix production of vocal fold scar fibroblasts in rats Pubmed: 24077847
J Voice. Vocal Fold Fibroblast Response to Growth Factor Treatment is Age Dependent: Results From an In Vitro Study Pubmed: 24495429
Arch Oral Biol. Porphyromonas gingivalis LPS inhibits osteoblastic differentiation and promotes pro-inflammatory cytokine production in human periodontal ligament stem cells. Pubmed: 24370188
Laryngoscope. Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria Pubmed:25545625
UNIVERSA MEDICINA Allogeneic human dermal fibroblasts are viable in peripheral blood mononuclear co-culture Univmed:Source
International Journal of Neuropsychopharmacology The vitamin D receptor agonist, calcipotriol, modulates fibrogenic pathways mitigating liver fibrosis in-vivo: An experimental study. pubmed:27477355
National Natural Scientific Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas after Chronic Alcohol Exposure pubmed:29121396
Nephron. Prevention of Diabetic Nephropathy by Modified Acidic Fibroblast Growth Factor pubmed:28768285
Cell and Tissue Research Effect of TGFβ1, TGFβ3 and keratinocyte conditioned media on functional characteristics of dermal fibroblasts derived from reparative (Balb/c) and … Pubmed:29637306
International Journal of Molecular Medicine LOXL2, a copper-dependent monoamine oxidase, activates lung fibroblasts through the TGF-β/Smad pathway Pubmed: 30320382
International Journal of Molecular Sciences Association between Plasma HMGB-1 and Silicosis: A Case-Control Study Pubmed: 30558126
Journal of Proteomics Salivary proteins from dysplastic leukoplakia and oral squamous cell carcinoma and their potential for early detection Pubmed: 31706945
Brazilian Journal of Pharmaceutical Sciences Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm
Ceramics International Platinum nanoparticles supported on functionalized hydroxyapatite: Anti-oxidant properties and bone cells response
Scientific reports Inhibition of eEF2K synergizes with glutaminase inhibitors or 4EBP1 depletion to suppress growth of triple-negative breast cancer cells 33911160
Int J Mol Sci Antiosteoporotic Nanohydroxyapatite Zoledronate Scaffold Seeded with Bone Marrow Mesenchymal Stromal Cells for Bone Regeneration: A 3D In Vitro Model Pubmed:35682677
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
EPA350Hu61 Eukaryotic Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA350Hu04 Recombinant Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
EPA350Hu62 Eukaryotic Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA350Hu03 Recombinant Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA350Hu01 Recombinant Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
APA350Hu61 Active Collagen Type I Alpha 1 (COL1a1) Cell culture; Activity Assays.
RPA350Hu02 Recombinant Collagen Type I Alpha 1 (COL1a1) Positive Control; Immunogen; SDS-PAGE; WB.
CPA350Hu11 BSA Conjugated Collagen Type I Alpha 1 (COL1a1) Immunogen; SDS-PAGE; WB.
CPA350Hu21 OVA Conjugated Collagen Type I Alpha 1 (COL1a1) Immunogen; SDS-PAGE; WB.
PAA350Hu01 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC; ICC; IP.
PAA350Hu03 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC; ICC; IP.
PAA350Hu04 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC; ICC; IP.
PAA350Hu08 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC; ICC; IP.
PAA350Hu02 Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB
MAA350Hu22 Monoclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB
MAA350Hu21 Monoclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC
MAA350Hu23 Monoclonal Antibody to Collagen Type I Alpha 1 (COL1a1) WB; IHC; ICC; IP.
FAA350Hu02 Anti-Collagen Type I Alpha 1 (COL1a1) Monoclonal Antibody Flow cytometry.
SEA350Hu ELISA Kit for Collagen Type I Alpha 1 (COL1a1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA350Hu Multiplex Assay Kit for Collagen Type I Alpha 1 (COL1a1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.