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Monoclonal Antibody to Cluster Of Differentiation 146 (CD146)

MCAM; MUC18; Melanoma Cell Adhesion Molecule; Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; S-endo 1 endothelial-associated antigen

  • Product No.MAB670Hu22
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 106  US$ 246  US$ 352  US$ 880  US$ 3520 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CD146. It has been selected for its ability to recognize CD146 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Clinical Rheumatology Evaluation of various endothelial biomarkers in ankylosing spondylitis PubMed: 21556780
Inflammation The Effect of Regular Colchicine Treatment on Biomarkers Related with Vascular Injury in Newly Diagnosed Patients with Familial Mediterranean Fever SpringerLink: m7128503g576w808
Oncotarget Selective targeting of liver cancer with the endothelial marker CD146 Pubmed:25238265
Future Medicine Melanoma cell adhesion molecule as an emerging biomarker with prognostic significance in systolic heart failure pubmed:27355366
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APB670Hu01 Active Cluster Of Differentiation 146 (CD146) Cell culture; Activity Assays.
RPB670Hu01 Recombinant Cluster Of Differentiation 146 (CD146) Positive Control; Immunogen; SDS-PAGE; WB.
PAB670Hu01 Polyclonal Antibody to Cluster Of Differentiation 146 (CD146) WB; ICC/IF
FAB670Hu01 Anti-Cluster Of Differentiation 146 (CD146) Polyclonal Antibody FCM
FAB670Hu81 FITC-Linked Anti-Cluster Of Differentiation 146 (CD146) Polyclonal Antibody FCM
RAB670Hu21 Recombinant Antibody to Cluster Of Differentiation 146 (CD146) FCM
MAB670Hu22 Monoclonal Antibody to Cluster Of Differentiation 146 (CD146) WB; IHC; ICC; IP.
SEB670Hu ELISA Kit for Cluster Of Differentiation 146 (CD146) Enzyme-linked immunosorbent assay for Antigen Detection.
CMB670Hu Multiplex Assay Kit for Cluster Of Differentiation 146 (CD146) ,etc. by CBA (Cytometric Bead Array) FLIA Kit for Antigen Detection.
LMB670Hu Multiplex Assay Kit for Cluster Of Differentiation 146 (CD146) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.