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Recombinant High Temperature Requirement Factor A1 (HTRA1)

HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1

  • Product No.RPL604Co01
  • Organism SpeciesEscherichia coli Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass15.4kDa
  • Accurate Molecular Mass16kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla10~Gly146 with N-terminal His Tag
  • Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point5.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 176  US$ 440  US$ 880  US$ 2640  US$ 6600 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Placenta Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR PubMed: 23083999
Placenta Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia PubMed: 22964307
Exp Gerontol Association of frailty with the serine protease HtrA1 in older adults Pubmed:27058767
International Journal of Clinical and Experimental Pathology HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways files:ijcep0069706.pdf
Pregnancy Hypertension Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?
American journal of translational research HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathway Pubmed: 31497227
J Matern Fetal Neonatal Med First trimester HtrA1 maternal plasma level and spontaneous preterm birth Pubmed: 32102578
BMC Geriatr Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population 33743591
Catalog No. Related products for research use of Escherichia coli Organism species Applications (RESEARCH USE ONLY!)
RPL604Co02 Recombinant High Temperature Requirement Factor A1 (HTRA1) Positive Control; Immunogen; SDS-PAGE; WB.
RPL604Co01 Recombinant High Temperature Requirement Factor A1 (HTRA1) Positive Control; Immunogen; SDS-PAGE; WB.
PAL604Co01 Polyclonal Antibody to High Temperature Requirement Factor A1 (HTRA1) WB; IHC; ICC; IP.
PAL604Co02 Polyclonal Antibody to High Temperature Requirement Factor A1 (HTRA1) WB