Recombinant Fibroblast Growth Factor 15 (FGF15)

  • Product No.RPL154Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass24.1kDa
  • Accurate Molecular Mass24kDa(Analysis of differences refer to the manual)
  • Residues & TagsGly25~Lys218 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 172  US$ 430  US$ 860  US$ 2580  US$ 6450 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Endocrinology. Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21 PubMed: 25774553
Inflammatory Bowel Diseases Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation pubmed:27580383
J Lipid Res. Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis. pubmed:28130274
BMC Endocrine Disorders The relationship between bile acid concentration, glucagon-like-peptide 1, fibroblast growth factor 15 and bile acid receptors in rats during progression of glucose intolerance 10.1186/s12902-017-0211-5
Journal of Physiology and Biochemistry The ileal FGF15/19 to hepatic FGFR4 axis regulates liver regeneration after partial hepatectomy in mice Pubmed:29468415
Developmental Cell FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis Pubmed: 30745141
Endocrinology Interactions between the gravitostat and the fibroblast growth factor system for the regulation of body weight
Food & Function Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis Pubmed: 31626262
Journal of Translational Medicine Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation Pubmed: 33036625
Chin Med Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis 34736501
Int J Biol Sci Dynamics of the gut-liver axis in rats with varying fibrosis severity Pubmed:35637968
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
APL154Ra01 Active Fibroblast Growth Factor 15 (FGF15) Cell culture; Activity Assays.
RPL154Ra01 Recombinant Fibroblast Growth Factor 15 (FGF15) Positive Control; Immunogen; SDS-PAGE; WB.
PAL154Ra01 Polyclonal Antibody to Fibroblast Growth Factor 15 (FGF15) WB; IHC; ICC; IP.
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MAL154Ra23 Monoclonal Antibody to Fibroblast Growth Factor 15 (FGF15) WB; IHC; ICC; IP.
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MAL154Ra25 Monoclonal Antibody to Fibroblast Growth Factor 15 (FGF15) WB; IHC; ICC; IP.
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MAL154Ra21 Monoclonal Antibody to Fibroblast Growth Factor 15 (FGF15) WB; IHC; ICC; IP.
WEL154Ra Wide-range ELISA Kit for Fibroblast Growth Factor 15 (FGF15) Enzyme-linked immunosorbent assay for Antigen Detection.
SEL154Ra ELISA Kit for Fibroblast Growth Factor 15 (FGF15) Enzyme-linked immunosorbent assay for Antigen Detection.
CEL154Ra ELISA Kit for Fibroblast Growth Factor 15 (FGF15) Enzyme-linked immunosorbent assay for Antigen Detection.
LML154Ra Multiplex Assay Kit for Fibroblast Growth Factor 15 (FGF15) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSL154Ra01 ELISA Kit DIY Materials for Fibroblast Growth Factor 15 (FGF15) Main materials for "Do It(ELISA Kit) Yourself"