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Recombinant Chymase 1, Mast Cell (CMA1)

CYH; CYM; Alpha-chymase; Mast cell protease I

  • Product No.RPG515Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass23.7kDa
  • Accurate Molecular Mass24kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle22~Val197 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point9.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 188  US$ 470  US$ 940  US$ 2820  US$ 7050 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pathobiology Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells Karger: 000330169
Clinical and Experimental Metastasis Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer PubMed: 22552372
Mediators of Inflammation Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis Pubmed:25400334
Neurogastroenterology &amp; Motility Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery Pubmed:25677271
IJC Metab Endocr The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis PubMed: 26722642
Journal of Neuroinflammation Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food … Pubmed:29685134
Revista do Instituto de Medicina Tropical de São Paulo Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients Pubmed: 30365640
Science Advances Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury Pubmed: 32206714
Immunity Inflammation and Disease Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis Pubmed: 33016012
Microbiol Spectr Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome Pubmed:35612327
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPG515Ra01 Recombinant Chymase 1, Mast Cell (CMA1) Positive Control; Immunogen; SDS-PAGE; WB.
PAG515Ra01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
MAG515Ra21 Monoclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
SEG515Ra ELISA Kit for Chymase 1, Mast Cell (CMA1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMG515Ra Multiplex Assay Kit for Chymase 1, Mast Cell (CMA1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.