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Recombinant Chymase 1, Mast Cell (CMA1)

CYH; CYM; Alpha-chymase; Mast cell protease I

  • Product No.RPG515Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Cytoplasm
  • Predicted Molecular Mass28.7kDa
  • Accurate Molecular Mass29kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle22~Asn247 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01%skl, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point9.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 175  US$ 438  US$ 876  US$ 2628  US$ 6570 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pathobiology Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells Karger: 000330169
Clinical and Experimental Metastasis Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer PubMed: 22552372
Mediators of Inflammation Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis Pubmed:25400334
Neurogastroenterology &amp; Motility Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery Pubmed:25677271
IJC Metab Endocr The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis PubMed: 26722642
Journal of Neuroinflammation Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food … Pubmed:29685134
Revista do Instituto de Medicina Tropical de São Paulo Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients Pubmed: 30365640
Science Advances Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury Pubmed: 32206714
Immunity Inflammation and Disease Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis Pubmed: 33016012
Microbiol Spectr Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome Pubmed:35612327
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPG515Hu01 Recombinant Chymase 1, Mast Cell (CMA1) Positive Control; Immunogen; SDS-PAGE; WB.
PAG515Hu01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
PAG515Hu02 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
MAG515Hu21 Monoclonal Antibody to Chymase 1, Mast Cell (CMA1) WB; IHC; ICC; IP.
SEG515Hu ELISA Kit for Chymase 1, Mast Cell (CMA1) Enzyme-linked immunosorbent assay for Antigen Detection.
CMG515Hu Multiplex Assay Kit for Chymase 1, Mast Cell (CMA1) ,etc. by CBA (Cytometric Bead Array) FLIA Kit for Antigen Detection.
LMG515Hu Multiplex Assay Kit for Chymase 1, Mast Cell (CMA1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.