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Recombinant Inducible T-Cell Co Stimulator (ICOS)

CD278; AILIM; Inducible T-Cell Costimulator; Activation-Inducible Lymphocyte Immunomediatory Molecule

  • Product No.RPA777Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass12.2kDa
  • Accurate Molecular Mass12kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsn35~Ile131 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point7.8
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 168  US$ 420  US$ 840  US$ 2520  US$ 6300 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Archives of Dermatological Research Increased production of soluble inducible costimulator in patients with diffuse cutaneous systemic sclerosis Pubmed: 23053221
DNA Cell Biol. Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration. Pubmed: 24083358
Rheumatology Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis Pubmed: 23024058
Br J Haematol Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment Pubmed:34954822
Diagnostics (Basel) Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases Pubmed:35328257
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA777Mu01 Recombinant Inducible T-Cell Co Stimulator (ICOS) Positive Control; Immunogen; SDS-PAGE; WB.
PAA777Mu01 Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC; IP.
LAA777Mu71 Biotin-Linked Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC.