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Recombinant Activated Protein C (APC)

  • Product No.RPA738Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Massn/a
  • Accurate Molecular Massn/a(Analysis of differences refer to the manual)
  • Residues & TagsN-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Pointn/a
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • Downloadn/a
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 159  US$ 398  US$ 796  US$ 2388  US$ 5970 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
The Journal of Immunology Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice Jimmunol: 3413
Critical Care Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study BioMed: cc10553
Molecular Endocrinology Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period Endo: source
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study Sjtrem:1757-7241
Crit Care. Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation Pubmed:25260379
Am J Physiol Heart Circ Physiol. Monocytes regulate systemic coagulation and inflammation in abdominal sepsis Pubmed:25502108
Neuroscience Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model PubMed: 25936678
Journal of Intensive Care Activated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock Pubmed:26734467
Journal of Biological Chemistry Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells. JBC:Source
J Thromb Haemost A multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy Pubmed: 32480432
Validation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model 34021192
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA738Hu01 Recombinant Activated Protein C (APC) Positive Control; Immunogen; SDS-PAGE; WB.
PAA738Hu01 Polyclonal Antibody to Activated Protein C (APC) WB; IHC; ICC; IP.
SEA738Hu ELISA Kit for Activated Protein C (APC) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA738Hu High Sensitive ELISA Kit for Activated Protein C (APC) Enzyme-linked immunosorbent assay for Antigen Detection.