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Polyclonal Antibody to Activated Protein C (APC)
- Product No.PAA738Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen n/a
- Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
- TraitsLiquid
- Concentration500µg/mL
- Organism Species Moren/a
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 126
US$ 294
US$ 420
US$ 1050
US$ 4200
For more details, please contact local distributors!
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against APC. It has been selected for its ability to recognize APC in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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| Magazine | Citations |
| The Journal of Immunology | Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice Jimmunol: 3413 |
| Critical Care | Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study BioMed: cc10553 |
| Molecular Endocrinology | Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period Endo: source |
| Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study Sjtrem:1757-7241 |
| Crit Care. | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation Pubmed:25260379 |
| Am J Physiol Heart Circ Physiol. | Monocytes regulate systemic coagulation and inflammation in abdominal sepsis Pubmed:25502108 |
| Neuroscience | Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model PubMed: 25936678 |
| Journal of Intensive Care | Activated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock Pubmed:26734467 |
| Journal of Biological Chemistry | Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells. JBC:Source |
| J Thromb Haemost | A multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy Pubmed: 32480432 |
| Validation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model 34021192 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA738Hu01 | Recombinant Activated Protein C (APC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA738Hu01 | Polyclonal Antibody to Activated Protein C (APC) | WB; IHC; ICC; IP. |
| SEA738Hu | ELISA Kit for Activated Protein C (APC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEA738Hu | High Sensitive ELISA Kit for Activated Protein C (APC) | Enzyme-linked immunosorbent assay for Antigen Detection. |