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Polyclonal Antibody to Activated Protein C (APC)

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against APC. It has been selected for its ability to recognize APC in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
The Journal of Immunology Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice Jimmunol: 3413
Critical Care Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study BioMed: cc10553
Molecular Endocrinology Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period Endo: source
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study Sjtrem:1757-7241
Crit Care. Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation Pubmed:25260379
Am J Physiol Heart Circ Physiol. Monocytes regulate systemic coagulation and inflammation in abdominal sepsis Pubmed:25502108
Neuroscience Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model PubMed: 25936678
Journal of Intensive Care Activated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock Pubmed:26734467
Journal of Biological Chemistry Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells. JBC:Source
J Thromb Haemost A multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy Pubmed: 32480432
Validation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model 34021192
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
PAA738Hu01 Polyclonal Antibody to Activated Protein C (APC) WB; IHC; ICC; IP.
SEA738Hu ELISA Kit for Activated Protein C (APC) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA738Hu High Sensitive ELISA Kit for Activated Protein C (APC) Enzyme-linked immunosorbent assay for Antigen Detection.