Recombinant Vascular Cell Adhesion Molecule 1 (VCAM1)
CD106; INCAM-100; L1CAM
- Product No.RPA547Hu01
 - Organism SpeciesHomo sapiens (Human) Same name, Different species.
 - SourceProkaryotic expression
 - HostE.coli
 - Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
 - Subcellular LocationSecreted
 - Predicted Molecular Mass53.3kDa
 - Accurate Molecular Mass53kDa(Analysis of differences refer to the manual)
 - Residues & TagsGln109~Ser318 with N-terminal His and GST Tag
 - Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
 - Traits Freeze-dried powder
 - Purity> 90%
 - Isoelectric Point5.5
 - 
                        Applications
                        Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
 - UOM 10µg50µg 200µg 1mg 5mg
 - FOB
    
                                    US$ 120 
            
                
                        US$ 300 
                                        US$ 600 
                                        US$ 1800 
                                        US$ 4500 
                            
For more details, please contact local distributors! 
SEQUENCE
                                
                            USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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INCREMENT SERVICES
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                        Endotoxin Removal Kit
                                     - 
                    
                        BCA Protein Quantification Kit
                                     - 
                    
                        Protein Labeling Customized Service
                                     - 
                    
                        Molecular Mass Marker for Protein
                                     - 
                    
                        Recombinant Protein Customized Service
                                     - 
                    
                        Monoclonal Antibody Customized Service
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                        Polyclonal Antibody Customized Service
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                        Protein Activity Test Experiment Service
                                     - 
                    
                        Immunoprecipitation (IP) Experiment Service
                                     - 
                    
                        Buffer
                                     - 
                    
                        Endotoxin Removal Kit II
                                     - 
                    
                        Real Time PCR Experimental Service
                                     - 
                    
                        Spike RBD Protein (S-RBD)
                                     - 
                    
                        Protein G
                                     - 
                    
                        Protein A
                                     
| Magazine | Citations | 
| Amran et al. Lipids in Health and Disease | Changes in the vascular cell adhesion molecule-1, intercellular adhesion molecule-1 and c-reactive protein following administration of aqueous extract of piper sarmentosum on experimental. BioMed: 1476511X | 
| Vascular Pharmacology | Long-term ethanol consumption initiates atherosclerosis in rat aorta through inflammatory stress and endothelial dysfunction ScienceDirect: S1537189112000705 | 
| Canadian Journal of Physiology and Pharmacology | Resveratrol abrogates adhesion molecules and protects against TNBS-induced ulcerative colitis in rats. PubMed: 22029500 | 
| British Journal of Medical and Health Sciences | EFFECTS OF ADRIAMYCIN, CISPLATIN, AND 5-FLUOROURACIL ON THE TESTES OF ALBINO RATS Researchgate: Source | 
| Endocrine Metabolic & Immune Disordors Drug Targets. | Active immunization against tumor necrosis factor-alpha decreases proinflammatory cytokines, oxidative stress mediators and adhesion molecules risk factors in streptozotocin-induced diabetic rats. Pubmed: 23859636 | 
| Atherosclerosis | Increased monocyte adhesion by endothelial expression of VCAM-1 missense variation in vitro Pubmed: 24075742 | 
| Atherosclerosis | Activation of receptor for advanced glycation end products contributes to aortic remodeling and endothelial dysfunction in sinoaortic denervated rats. Pubmed: 23880178 | 
| BioMed research international | Endothelial gene expression and molecular changes in response to radiosurgery in in vitro and in vivo models of cerebral arteriovenous malformations Pubmed: 24199192 | 
| Arch Dis Child | PO-0699 Estimation Of Adhesion Molecules Intrauterine Growth Retardation (iugr) Newborns Bmj:Source | 
| Arch Dis Child? | PO-0701 Causes Of Fetal Growth Restriction And Early Neonatal Outcome Bmj:Source | 
| Arch Dis Child | PO-0698 Neonatal Resuscitation Practices In The Delivery Room In India: An Audit Using Videography Bmj:Source | 
| Naunyn-Schmiedeberg's Archives of Pharmacology | Insights into the antiatherogenic molecular mechanisms of andrographolide against?Porphyromonas gingivalis-induced atherosclerosis in rabbits Pubmed:25172523 | 
| Nutr Res. | Curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hypercholesterolemic rabbits Pubmed:25282128 | 
| Alexandria Journal of Medicine | Effect of consumption of fresh and heated virgin coconut oil on the blood pressure and inflammatory biomarkers: An experimental study in Sprague Dawley rats Sciencedirect:S2090506814000268 | 
| Canadian Journal of Physiology and Pharmacology | Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism Doi: Abs | 
| Hum Exp Toxicol | Effect of agmatine on experimental vascular endothelial dysfunction PubMed: 26424770 | 
| International Journal of Food Sciences and Nutrition | Serum lipid profile and inflammatory markers in the aorta of cholesterol-fed rats supplemented with extra virgin olive oil, sunflower oils and oil-products PubMed: 26401576 | 
| J Trace Elem Med Biol | Comparative angioprotective effects of magnesium compounds PubMed: 25127069 | 
| J Mol Cell Cardiol | Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation PubMed: 26231083 | 
| Endocrine | Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways Pubmed:26758998 | 
| Mol Neurobiol | A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats Pubmed:26867655 | 
| Pakistan journal of pharmaceutical sciences | Changes in blood pressure, vascular reactivity and inflammatory biomarkers following consumption of heated corn oil. pubmed:29084680 | 
| Acta Biochim Biophys Sin | Therapeutic potential of mesenchymal stem cells in acute kidney injury is affected by administration timing pubmed:28338909 | 
| Experimental and Therapeutic Medicine | Epigallocatechin‑3‑gallate attenuates neointimal hyperplasia in a rat model of carotid artery injury by inhibition of high mobility group box 1 expression pubmed:28962112 | 
| Experimental Parasitology | Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis pubmed:28821422 | 
| Evidence-Based Complementary and Alternative Medicine | BuShenKangShuai tablet reduces atherosclerotic lesion by improving blood lipids metabolism and inhibiting inflammatory response via TLR4 and NF-κB signaling pathway journals:1758383 | 
| Journal of Chromatography A | Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis S0021967317311858 | 
| International Journal of Clinical and Experimental Pathology | Protective effect of high mobility group box-1 silence on diabetic retinopathy: an in vivo study ISSN:1936-2625/IJCEP0055881 | 
| ResearchGate | Significance of Soluble Endoglin as a Possible Marker of Cardiovascular Disease in Type 2 Diabetic Patients 315113405 | 
| Regenerative Biomaterials | The directional migration and differentiation of mesenchymal stem cells toward vascular endothelial cells stimulated by biphasic calcium phosphate ceramic 10.1093/rb/rbx028 | 
| Anesthesiology | Vasculotide, an angiopoietin-1 mimetic, restores microcirculatory perfusion and microvascular leakage and decreases fluid resuscitation requirements in … Pubmed:28968277 | 
| PLoS Neglected Tropical Diseases | Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia … Pubmed:29522521 | 
| Life Sciences | Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects Pubmed:30012474 | 
| Evidence-based Complementary and Alternative Medicine | Bushenkangshuai Tablet Reduces Atherosclerotic Lesion by Improving Blood Lipids Metabolism and Inhibiting Inflammatory Response via TLR4 and NF-κB Signaling … Pubmed:29619063 | 
| Nutrition & Metabolism | L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women Pubmed: 30485835 | 
| Cytokine | Intercellular adhesion molecule-1 (ICAM-1) associates with 24-hour ambulatory blood pressure variability in type 2 diabetes and controls Pubmed: 30716657 | 
| Anticancer Research | Effect of Radiation on the Expression of CVD-related miRNAs, Inflammation and Endothelial Dysfunction of HUVECs Pubmed: 30711956 | 
| European Journal of Pharmacology | The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in … Pubmed: 30826323 | 
| international journal of molecular sciences | Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells Pubmed: 31671764 | 
| Archives of Insect Biochemistry and Physiology | Vanadyl sulphate ameliorates biomarkers of endothelial injury and coagulation and thrombosis in a rat model of hyperglycaemia Pubmed: 31774317 | 
| BMC Endocrine Disorders | The role of the adipocytokines vaspin and visfatin in vascular endothelial function and insulin resistance in obese children Pubmed: 31771561 | 
| Scientific Reports | Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea Pubmed: 31882827 | 
| BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE | Endothelial epithelial sodium channel involves in high-fat diet-induced atherosclerosis in low-density lipoprotein receptor-deficient mice Pubmed: 33065235 | 
| Antioxidants (Basel) | Anti-Atherogenic Effects of Orlistat on Obesity-Induced Vascular Oxidative Stress Rat Model 33562069 | 
| Sci. Pharm | Dehydroepiandrosterone (DHEA) Improves the Metabolic and Haemostatic Disturbances in Rats with Male Hypogonadism | 
| Journal of the South African Veterinary Association | Circulating markers of endothelial activation in canine parvoviral enteritis | 
        
                                
                            
