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Recombinant Matrix Metalloproteinase 12 (MMP12)

MME; HME; ME; Macrophage Metalloelastase; Macrophage Elastase

  • Product No.RPA402Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Predicted Molecular Mass22.9kD
  • Accurate Molecular Mass23kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla290-Gly469 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point9.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 192  US$ 480  US$ 960  US$ 2880  US$ 7200 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International journal of colorectal disease Expression and inhibition of matrix metalloproteinase (MMP)-8, MMP-9 and MMP-12 in early colonic anastomotic repair Pubmed: 23619615
Thromb Haemost. Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke Pubmed:24671655
American Journal of Physiology - Lung Cellular and Molecular Physiology Inspiratory resistive breathing induces MMP-9 and MMP-12 expression in the lung Pubmed:25595645
Photodermatol Photoimmunol Photomed. Protective effects of Aloe sterols against UVB‐induced photoaging in hairless mice pubmed:27995657
Яковлева Наталья Юрьевна
Identification of Polyphenolic Compounds and Hepatoprotective Activity of Artichoke (Cynara Scolymus L.) Edible Part Extracts in Rats
Nat Commun Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice Pubmed:35031603
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA402Hu01 Recombinant Matrix Metalloproteinase 12 (MMP12) Positive Control; Immunogen; SDS-PAGE; WB.
PAA402Hu01 Polyclonal Antibody to Matrix Metalloproteinase 12 (MMP12) WB; IHC; ICC/IF
LAA402Hu71 Biotin-Linked Polyclonal Antibody to Matrix Metalloproteinase 12 (MMP12) WB
LAA402Hu81 FITC-Linked Polyclonal Antibody to Matrix Metalloproteinase 12 (MMP12) WB; IHC; ICC; IF.
MAA402Hu22 Monoclonal Antibody to Matrix Metalloproteinase 12 (MMP12) WB; IHC; ICC; IP.
SEA402Hu ELISA Kit for Matrix Metalloproteinase 12 (MMP12) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA402Hu Multiplex Assay Kit for Matrix Metalloproteinase 12 (MMP12) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.