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Recombinant Cathepsin K (CTSK)

CTS-K; CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD; Pycnodysostosis; Cathepsin O; Cathepsin X

  • Product No.RPA267Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome
  • Predicted Molecular Mass27.2kDa
  • Accurate Molecular Mass30kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla115~Met329 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point9.0
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 183  US$ 458  US$ 916  US$ 2748  US$ 6870 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Acta Histochemica MRMT-1 rat breast carcinoma cells and models of bone metastases: improvement of an in vitro system to mimic the in vivo condition. PubMed: S0065128112000773
Atherosclerosis.? Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid artery Pubmed:24534452
Genet. Mol. Res Drynaria total flavonoids decrease cathepsin K expression in ovariectomized rats Pubmed:25036175
Age (Dordr) In vitro method for the screening and monitoring of estrogen-deficiency osteoporosis by targeting peripheral circulating monocytes PubMed: 26250906
Journal of Infectious Diseases Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis PubMed: 26416658
PLoS One. Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis pmc:PMC4822855
Cell Death And Differentiation TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42 Pubmed:29358671
Indian Journal of Dental Research Comparative evaluation of cathepsin K levels in gingival crevicular fluid among smoking and nonsmoking patients with chronic periodontitis Pubmed: 30409937
International Journal of Biological Macromolecules A bioactive exopolysaccharide from marine bacteria Alteromonas sp. PRIM-28 and its role in cell proliferation and wound healing in vitro Pubmed: 30851325
毕业论文 Biomarkers of Compromised Implant Fixation
neuroscience letters Compound K induces neurogenesis of neural stem cells in thrombin induced nerve injury through LXRα signaling in mice Pubmed: 32371156
Информационный алгоритм неинвазивной оценки остеорезорбтивного побочного действия глюкокортикостероидов у больных язвенным колитом
Особенности остеоиммунологических аспектов остеорезорбции при периимплантите, хроническом пародонтите и раке альвеолярного отростка и …
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