Recombinant Paraoxonase 1 (PON1)
ESA; PON; Esterase A; Serum paraoxonase/arylesterase 1; Aromatic esterase 1; A-esterase 1; Serum aryldialkylphosphatase 1
- Product No.RPA243Ra02
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted
- Predicted Molecular Mass42.9kDa
- Accurate Molecular Mass41kDa(Analysis of differences refer to the manual)
- Residues & TagsAla2~Leu355 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder
- Purity> 80%
- Isoelectric Point4.9
-
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 197
For more details, please contact local distributors! US$ 492 US$ 984 US$ 2952 US$ 7380
SEQUENCE
![](/upload/product/pictures/RPA243Ra02-202203231546137919.jpg)
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
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Endotoxin Removal Kit
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Recombinant Protein Customized Service
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Buffer
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Endotoxin Removal Kit II
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
Magazine | Citations |
Digestive Diseases and Sciences | Fatty Liver Is Associated with Recurrent Bacterial Infections Independent of Metabolic Syndrome PubMed: 20205513 |
Clinica Chimica Acta | Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome PubMed: 21704607 |
Journal of Laparoendoscopic & Advanced Surgical Techniques | Combined Serum Proteomic and Metabonomic Profiling After Laparoscopic Sleeve Gastrectomy in Children and Adolescents Wiley: source |
PLoS One. | High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy PubMed: 21887280 |
Atherosclerosis | Macrophage cholesterol efflux to plasma and HDL in subjects with low and high homocysteine levels: a FIELD substudy PubMed: 21696738 |
Lipids in Health and Disease | Beneficial effects of omega-3 fatty acids in the proteome of high-density lipoprotein proteome PubMed: PMC3480889 |
British Journal of Nutrition | Extra-virgin olive oil consumption reduces the age-related decrease in HDL and paraoxonase 1 anti-inflammatory activities Pubmed: 23510814 |
Diabetes & Metabolic Syndrome | Paraoxonase 1: A better atherosclerotic risk predictor than HDL in type 2 diabetes mellitus Pubmed: 23680251 |
Redox Report | Paraoxonase responses to exercise and niacin therapy in men with metabolic syndrome Pubmed:25180827 |
Toxicol Ind Health. | Influence of α-tocopherol and α-lipoic acid on bisphenol-A-induced oxidative damage in liver and ovarian tissue of rats Pubmed:25548375 |
RETOS. Nuevas Tendencias en Educación Física, Deporte y Recreación | A single session of aerobic exercise influences paraoxonase 1 activity and concentration Articulo: 345738764042 |
PLoS One | Plasma Protein Biomarkers of Hepatocellular Carcinoma in HCV-Infected Alcoholic Patients with Cirrhosis PubMed: 25789864 |
Renal Failure | Association of lipid profile with serum PON1 concentration in patients with chronic kidney disease Pubmed:26888625 |
Pharmacological reports | The Role of PON-1, GR, IL-18, and oxLDL in Depression With and Without Posttraumatic Stress Disorder science:article |
Clinical and Experimental Hypertension | Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension pubmed:27668323 |
Diabetes & Metabolic Syndrome: Clinical Research & Reviews | Paraoxonase-1 is a better indicator than HDL of Atherosclerosis-A pilot Study in North Indian population pubmed:29254890 |
Diabetes/Metabolism Research and Reviews | A Case-control Study: The Association of Serum Paraoxonase 1 Activity and Concentration with the Development of Type 2 Diabetes Mellitus pubmed:29156090 |
Journal of Chromatography A | Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis S0021967317311858 |
Pharmacological Reports | The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder. pubmed:28623707 |
American Journal of Food Science and Health | Palm Wine and Orijin Bitters Severed Hyperlipidemia and Immunomodulatory Responses in Atherogenic-diet Fed Male Wistar Rats ISSN: 2381-7224 |
Metabolic brain disease | Individuals with autism have higher 8-Iso-PGF2α levels than controls, but no correlation with quantitative assay of Paraoxonase 1 serum levels pubmed:28808839 |
Therapeutic Apheresis And Dialysis | Serum Endocan Levels are Associated With Paraoxonase 1 Concentration in Patients With Chronic Kidney Disease Pubmed:29368426 |
Biological Trace Element Research | Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in Rats Pubmed: 30251228 |
GLYCOCONJUGATE JOURNAL | Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer Pubmed: 30607521 |
Hematology. | Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails Pubmed: 30661467 |
Proteomics Clinical Applications | Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828 |
Environment International | Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures Pubmed: 31639605 |
Nutrition, Metabolism and Cardiovascular Diseases | Phenotypes and concentration of PON1 in cardiovascular disease: the role of nutrient intake Pubmed: 31757567 |
Environment International | Estimating renal and hepatic clearance rates of organophosphate esters in humans: Impacts of intrinsic metabolism and binding affinity with plasma proteins Pubmed: 31783242 |
RESPIRATORY RESEARCH | The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation … Pubmed: 33148285 |
CLINICAL RHEUMATOLOGY | PON-1 haplotype (-108C> T, L55M, and Q192R) modulates the serum levels and activity PONase promoting an atherogenic lipid profile in rheumatoid arthritis patients Pubmed: 32556934 |
respiratory research | The adverse alterations of HDL in quality promote septic ARDS via exacerbated pulmonary endothelial dysfunction |
J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555 |
PLoS One | Vitamin D status and systemic redox biomarkers in adults with obesity 30973911 |
Oxid Med Cell Longev | Repetitions of Strenuous Exercise Consistently Increase Paraoxonase 1 Concentration and Activity in Plasma of Average-Trained Men 34917230 |
Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
RPA243Ra01 | Recombinant Paraoxonase 1 (PON1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA243Ra03 | Recombinant Paraoxonase 1 (PON1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA243Ra04 | Recombinant Paraoxonase 1 (PON1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA243Ra02 | Recombinant Paraoxonase 1 (PON1) | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA243Ra01 | Polyclonal Antibody to Paraoxonase 1 (PON1) | WB; IHC; ICC; IP. |
PAA243Ra02 | Polyclonal Antibody to Paraoxonase 1 (PON1) | WB; IHC; ICC; IP. |
LAA243Ra71 | Biotin-Linked Polyclonal Antibody to Paraoxonase 1 (PON1) | WB; IHC; ICC. |
LAA243Ra51 | APC-Linked Polyclonal Antibody to Paraoxonase 1 (PON1) | WB; IHC; ICC; IF. |
MAA243Ra21 | Monoclonal Antibody to Paraoxonase 1 (PON1) | WB; IHC; ICC; IP. |
SEA243Ra | ELISA Kit for Paraoxonase 1 (PON1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA243Ra | Multiplex Assay Kit for Paraoxonase 1 (PON1) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |
KSA243Ra01 | ELISA Kit DIY Materials for Paraoxonase 1 (PON1) | Main materials for "Do It (ELISA Kit) Yourself". |