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Recombinant Matrix Metalloproteinase 8 (MMP8)

CLG2; HNC; PMNL-CL; Collagenase 2; Neutrophil Collagenase; PMNL collagenase

  • Product No.RPA103Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Predicted Molecular Mass31.3kDa
  • Accurate Molecular Mass38kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu211~Ser449 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 180  US$ 450  US$ 900  US$ 2700  US$ 6750 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
PLoS ONE A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches Plosone: Source
Journal of Periodontology Effects of Photodynamic Therapy on the Clinical and Gingival Crevicular Fluid Inflammatory Biomarkers in Chronic Periodontitis: A Split-Mouth Randomized Clinical Trial Joponline: 130464
Thromb Haemost. Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke Pubmed:24671655
An Experimental Model for Inducing Periodontal Pathology in Rat: Histopathological and Enzymatic Aspects Usamvcluj:Source
Journal of Molecular and Cellular Cardiology Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury Pubmed:27056420
J Periodontal Implant Sci Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol pmc:PMC4848383
Int Wound J. From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. Pubmed:26991748
Eur J Clin Invest.  Alamandine abrogates neutrophil degranulation in atherosclerotic mice. pubmed:27930810
International Wound Journal From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases pubmed:26991748
Medicine (Baltimore) Rapid detection of urinary soluble intercellular adhesion molecule-1 for determination of lupus nephritis activity Pubmed:29953010
Scientific Reports Atherosclerotic plaque vulnerability is increased in mouse model of lupus Pubmed: 33110193
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPA103Ra01 Recombinant Matrix Metalloproteinase 8 (MMP8) Positive Control; Immunogen; SDS-PAGE; WB.
RPA103Ra02 Recombinant Matrix Metalloproteinase 8 (MMP8) Positive Control; Immunogen; SDS-PAGE; WB.
PAA103Ra01 Polyclonal Antibody to Matrix Metalloproteinase 8 (MMP8) WB; IHC; ICC; IP.
MAA103Ra22 Monoclonal Antibody to Matrix Metalloproteinase 8 (MMP8) WB; IHC; ICC; IP.
MAA103Ra21 Monoclonal Antibody to Matrix Metalloproteinase 8 (MMP8) WB; IHC; ICC; IP.
SEA103Ra ELISA Kit for Matrix Metalloproteinase 8 (MMP8) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA103Ra CLIA Kit for Matrix Metalloproteinase 8 (MMP8) Chemiluminescent immunoassay for Antigen Detection.
LMA103Ra Multiplex Assay Kit for Matrix Metalloproteinase 8 (MMP8) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.