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Recombinant Angiopoietin 1 (ANGPT1)

ANG1; AGP1; AGPT; ANG-I

  • Product No.RPA008Po01
  • Organism SpeciesSus scrofa; Porcine (Pig) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass19.4kDa
  • Accurate Molecular Mass19kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg284~Cys452 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 164  US$ 410  US$ 820  US$ 2460  US$ 6150 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Theriogenology Evaluation of Changes in Doppler Ultrasonography Indices and Levels of Maternal Serum Angiogenic Factors throughout Pregnancy in Ewes Science: Article
J Atheroscler Thromb High Mobility Group Box 1 Promotes Angiogenesis from Bone Marrow-derived Endothelial Progenitor Cells after Myocardial Infarction PubMed: 25735431
Archives of Biological Sciences Diabetes-induced renal failure is associated with tissue inflammation and neutrophil gelatinase-associated lipocalin: Effects of resveratrol publication:299492265_Diabetes-induced_renal_failu
Am J Transl Res Angiopoietin-1 facilitates recovery of hematopoiesis in radiated mice Pubmed:27347310
Clinical research Increased plasma concentrations of interleukin 35 in patients with coronary artery disease Journal:-19
Turkish Journal of Medicl Sciences A new angiogenesis prognostic index with VEGFA, PlGF, and angiopoietin 1 predicts survival in patients with advanced gastric cancer pubmed:28425270
Sci Rep.  Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis. pubmed:28276491
PeerJ  The ratio of serum Angiopoietin-1 to Angiopoietin-2 in patients with cervical cancer is a valuable diagnostic and prognostic biomarker pubmed:28584715
Molecular&cellular proteomics Prediction of Response to Sorafenib in Hepatocellular Carcinoma: A Marker Panel by Multiple Reaction Monitoring-Mass Spectrometry pubmed:28550167
Tumor Biology Cervical cancer cell–derived angiopoietins promote tumor progression pubmed:28720059
Free Patents online RHEUMATOID ARTHRITIS RELATED BIOMARKER 20170350884
Anesthesiology Vasculotide, an angiopoietin-1 mimetic, restores microcirculatory perfusion and microvascular leakage and decreases fluid resuscitation requirements in … Pubmed:28968277
British Journal of Anaesthesia Vasculotide, an angiopoietin-1 mimetic, reduces pulmonary vascular leakage and preserves microcirculatory perfusion during cardiopulmonary bypass in rats 10.1016:j.bja.2018.05.049
The Journal of Biological Chemistry Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice Pubmed:29929978
Clinical Significance of Nectin-4 Expression in Metastasis and Angiogenesis for Tumor Relapse Doi: 10.4143/crt.2018.214
BIOLOGY OF REPRODUCTION Prostaglandin-mediated effects in early canine corpus luteum: In vivo effects on vascular and immune factors Pubmed: 30929911
Scientific Reports Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea Pubmed: 31882827
Biochem Biophys Res Commun Effects of interleukin-6 and tumor necrosis factor-α on the expression of angiogenic and collagenolytic factors in premature and mature adipocytes Pubmed: 32800538
J Nutr Biochem Effects of protein malnutrition on haematopoietic regulatory activity of bone marrow mesenchymal stem cells 33705953
Intensive Care Med Exp The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats 33997943
Gynecol Endocrinol Potential of thrombospondin-1 in treatment of polycystic ovary syndrome rat model: a preliminary study 34282706
Yonsei Med J RAR-Related Orphan Receptor: An Accelerated Preeclampsia Progression by Activating the JAK/STAT3 Pathway Pubmed:35619579
Catalog No. Related products for research use of Sus scrofa; Porcine (Pig) Organism species Applications (RESEARCH USE ONLY!)
RPA008Po01 Recombinant Angiopoietin 1 (ANGPT1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA008Po01 Polyclonal Antibody to Angiopoietin 1 (ANGPT1) WB; IHC; ICC; IP.