Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2)

IPOA1; QIP2; RCH1; SRP1alpha; RAG Cohort 1; Importin Alpha 1; RAG cohort protein 1; SRP1-alpha

SPECIFITY

The antibody is a mouse monoclonal antibody raised against KPNa2. It has been selected for its ability to recognize KPNa2 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence:5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Oncol Rep.? KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferation Pubmed:25109899
Tumor Biology KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosis pubmed:28651492
Head & Neck Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin‐1β‐induced matrix metalloproteinase expression in oral cancer Pubmed:29542209
International Journal of Cancer Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers 34591985
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