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Karyopherin Alpha 2 (KPNa2)

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IPOA1; QIP2; RCH1; SRP1alpha; RAG Cohort 1; Importin Alpha 1; RAG cohort protein 1; SRP1-alpha

Karyopherin Alpha 2 (KPNa2)
CCC E748
HGNC 6395
MGI 103561
PubMed 16188882
RGD 621419
UniProt P52292
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE748Hu01 Recombinant Karyopherin Alpha 2 (KPNa2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE748Hu01 Polyclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB,IHC,ICC/IF; FCM
MAE748Hu21 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; ICC/IF;FCM
MAE748Hu22 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; IHC; ICC; IP.
MAE748Hu23 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; IHC
MAE748Hu24 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; IHC; ICC; IP.
MAE748Hu25 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; IHC
MAE748Hu26 Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) WB; IHC; ICC; IP.
Assay Kits SEE748Hu ELISA Kit for Karyopherin Alpha 2 (KPNa2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Karyopherin Alpha 2 (KPNa2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Karyopherin Alpha 2 (KPNa2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Karyopherin Alpha 2 (KPNa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Karyopherin Alpha 2 (KPNa2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Karyopherin Alpha 2 (KPNa2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Karyopherin Alpha 2 (KPNa2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Karyopherin Alpha 2 (KPNa2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Karyopherin Alpha 2 (KPNa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Karyopherin Alpha 2 (KPNa2) ELISA Kit Customized Service Offer
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