≡

Eukaryotic Interleukin 2 (IL2)

TCGF; Lymphokine; T-Cell Growth Factor; Aldesleukin

  • Product No.EPA073Hu61
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceEukaryotic expression
  • Host293F cell
  • Endotoxin Level<1.0EU per 1ug (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass17.0kDa
  • Accurate Molecular Mass18kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla21~Thr153 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point7.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 244  US$ 610  US$ 1220  US$ 3660  US$ 9150 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journal of Medicinal Plants Research Evaluation of water plantain (Alisma canaliculatum A. Br. et Bouche) and mistletoe (Viscum album L.) effects on broiler growth performance, meat composition and serum biochemical parameters AcadeMic: source
Bone Synthesis and inflammatory response of a novel silk fibroin scaffold containing BMP7 adenovirus for bone regeneration PubMed: 22796416
Nanomedicine Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform PubMed: 23394132
Food and Chemical Toxicology Identification and functional characterization of a novel fungal immunomodulatory protein from Postia placenta Pubmed:25662032
Pharmaceutical Research Molecular Mechanisms of the Modulatory Effect of Vitamin E on Tacrolimus (FK506)-Induced Renal Injury in Rats Openview: 6Ba34F298130121B36Fc3E227Ed416F4
PLoS Neglected Tropical Diseases Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice PubMed: 26352932
Int J Clin Exp Med Berberine alleviates preeclampsia possibly by regulating the expression of interleukin-2/interleukin-10 and Bcl-2/Bax PubMed: 26629148
Clin Oral Investig Can apical periodontitis affect serum levels of CRP, IL-2, and IL-6 as well as induce pathological changes in remote organs? PubMed: 26556576
veterinary research forum Evaluation of proliferation and cytokines production by mitogen-stimulated bovine peripheral blood mononuclear cells Article_14936_6.Html:
Pharmaceutical Biology Molecular mechanisms of the protective role of wheat germ oil against cyclosporin A-induced hepatotoxicity in rats PubMed: 25858514
Immunologic Research Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE10 and is crucial for liver transplant tolerance PubMed: 25982596
J Reprod Immunol The immunomodulating effect of seminal plasma on T cells PubMed: 25799173
удк Циток Cgi-Bin: Irbis_Nbuv
Biomark Med Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinoma PubMed: 26609634
Environmental Science and Pollution Research Ameliorative effect of flaxseed oil against thiacloprid-induced toxicity in rats: hematological, biochemical, and histopathological study Pubmed:26957428
Advances in Experimental Medicine and Biology  Antiinflammatory Effect of N-Acetylcysteine Combined with Exogenous Surfactant in Meconium-Induced Lung Injury Pubmed:27283193
Research in Veterinary Science Effects of feed supplementation with glycine chelate and iron sulfate on selected parameters of cell-mediated immune response in broiler chickens Pubmed:27473977
Biomedicine & Pharmacotherapy Investigation of the anti-glioma activity of Oviductus ranae protein hydrolysate Pubmed:27261592
Int J Pharm Bio Sci International Journal of Pharma and Bio Sciences ISSN cms:4987
Asian J Pharm Clin Res INFLUENCE OF ZINCOVIT DROP (NUTRITIONAL FOOD SUPPLEMENT) ON IMMUNE SYSTEM IN NORMAL AND CYCLOPHOSPHAMIDE INTOXICATED WISTAR RATS journals:3790
United States Patent Application HERPES VIRUS VACCINES AND TREATMENTS y2016:0067330.html
BMC Veterinary Research Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis pubmed:27553600
Vaccine. Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J. pubmed:28049588
Taylor & Francis Influences of Hyriopsis cumingii polysaccharides on mice immunosignaling molecules and T lymphocyte differentiation 09540105.2017.1306494
Physiological Research Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. pubmed:28006947
Journal of Virology Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed:
 Research in Veterinary The effect of feed supplementation with zinc chelate and zinc sulphate on selected humoral and cell-mediated immune parameters and cytokine concentration in … S0034528816303162
Research in Veterinary Science Commercial gold nanocolloid inhibits synthesis of IL-2 and proliferation of porcine T lymphocytes science:article
Acta Vet Hung. Imbalance of intestinal immune function in piglets infected by porcine circovirus type 2 during the fetal period. pubmed:28244338
Домашня сторінка ВПЛИВ КРОВОВТРАТИ НА ДИНАМІКУ ВМІСТУ ЦИТОКІНІВ СИРОВАТКИ КРОВІ В ПЕРІОД ГОСТРОЇ РЕАКЦІЇ НА КРАНІОСКЕЛЕТНУ ТРАВМУ 83646
Journal of Agricultural and Food Chemistry Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathway pubmed:29032684
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs pubmed:28549299
poultry science The effect of feed supplementation with Zakarpacki zeolite (clinoptilolite) on percentages of T and B lymphocytes and cytokine concentrations in poultry pubmed:28339915
Journal of Animal Physiology and Animal Nutrition The effect of feed supplementation with a copper-glycine chelate and copper sulphate on selected humoral and cell-mediated immune parameters, plasma superoxide dismutase activity, ceruloplasmin and cytokine concentration in broiler chickens doi:10.1111
Molecular Medicine Reports Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury 10.3892/mmr.2017.6837
Veterinary Microbiology A bacterial ghost improves the immunological efficacy of a Newcastle disease virus inactivated vaccine pubmed:28619143
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-ݜ傠Signaling Pathway in Rats 10.1155/2017/3057268
Veterinary Immunology and Immunopathology Integrated effect of seasons and lactation stages on the plasma inflammatory cytokines, function and receptor expression of milk neutrophils in Sahiwal (Bos indicus) cows. pubmed:28895861
Biological Rhythm Research A study of altered cytokine rhythms associated with successful implantation in cows 10.1080/09291016.2017.1361159
Journal of Pain Research Sex differences in complex regional pain syndrome type I (CRPS-I) in mice pubmed:28831269
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats 10.1155/2017/3057268
In Vivo Study on the Hindrance Activity of Cinnamon Extract Against Aspergillus niger in Mice ISSN: 0974-4290
Cancer Science Sonodynamic therapy‐assisted immunotherapy: A novel modality for cancer treatment Pubmed:29575297
PLoS One Cyclosporine a drug-delivery system for high-risk penetrating keratoplasty: Stabilizing the intraocular immune microenvironment Pubmed:29734357
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … Pubmed:29305686
Microbial Pathogenesis Pathogen-dependent modulation of milk neutrophils competence, plasma inflammatory cytokines and milk quality during intramammary infection of Sahiwal (Bos … Pubmed:29787791
Theriogenology Effect of tropical thermal stress on peri-implantation immune responses in cows Pubmed:29625402
Food & Nutrition Research Immunomodulatory activity of Lactobacillus plantarum KLDS1. 0318 in cyclophosphamide-treated mice Pubmed:30026678
Journal of Animal Physiology and Animal Nutrition The effect of feed supplementation with a copper‐glycine chelate and copper sulphate on selected humoral and cell‐mediated immune parameters, plasma … Pubmed:28603872
Journal of International Medical Research Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease Pubmed:29950127
International Journal of Environmental Studies  Effectiveness of steamed and cooked broccoli to attenuate bone marrow injury and suppressed haemopoiesis in male rats exposed to petrol vapours 10.1080:00207233.2018.1502956
Veterinary Immunology and Immunopathology Evaluation of T regulatory lymphocytes and serum concentration of selected cytokines in dogs with perianal tumors
International Immunopharmacology Vitamin E inhibits cyclosporin A-induced CTGF and TIMP-1 expression by repressing ROS-mediated activation of TGF-β/Smad signaling pathway in rat liver Pubmed: 30391882
Journal of Veterinary Research Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle
Journal of Neuroinflammation Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell … Pubmed: 30823934
International Journal of Laboratory Hematology CD56 natural killer cells exhibit abnormal phenotype and function in severe aplastic anemia
International Immunopharmacology Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c mice Pubmed: 30974284
中国免疫学杂志 TRAF-6 调控TGF-β1-Smad2/Smad3 信号通路在Graves 病免疫发病机制中的作用
Animals Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training Pubmed: 31462005
Journal of Medicinal Food Polysaccharide from the Seeds of Plantago asiatica L. Protect Against Lipopolysaccharide-Induced Liver Injury Pubmed: 31560611
international urology and nephrology The therapeutic effect of dendritic cells expressing indoleamine 2, 3-dioxygenase (IDO) on an IgA nephropathy mouse model Pubmed: 31894556
Transboundary and Emerging Diseases Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in China Pubmed: 32187856
Nanomedicine The toxicity of alumina nanoparticles to immune system in mice Pubmed: 32162999
Immunopharmacol Immunotoxicol Cordycepin exhibits a suppressive effect on T cells through inhibiting TCR signaling cascade in CFA-induced inflammation mice model Pubmed: 32105161
Journal of Receptors and Signal Transduction Research Suppressor of ras val-2 promotes inflammation-mediated oxidative stress and cell apoptosis in cardiomyocytes through activating Mst1-mROS signaling pathway Pubmed: 32065019
Antibiotics Effects of Early Intervention with Antibiotics and Maternal Fecal Microbiota on Transcriptomic Profiling Ileal Mucusa in Neonatal Pigs Pubmed: 31963653
Bone Research Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis Pubmed: 32047705
JOURNAL OF CHEMOTHERAPY Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinoma Pubmed: 32930084
THERIOGENOLOGY Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasion Pubmed: 32810792
Theriogenology A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cows Pubmed: 32810791
Life Sci Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study Pubmed: 32652140
BIOLOGICAL TRACE ELEMENT RESEARCH Association Between Serum Selenium Level and Subclinical Mastitis in Dairy Cattle Pubmed: 32583225
IMMUNOSTIMULATORY EFFECT OF MORINGA OLEIFERA LEAVES EXTRACT ON CYCLOPHOSPHAMIDE-INDUCED IMMUNOSUPPRESSION IN MICE
ACS Biomaterials Science & Engineering Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction
Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study
Hormonal and Cytokine Blood Profile of Dairy Cows in the Early Gestation Period
THE CHANGE OF INDICATORS OF PROTEIN, LIPID AND CARBOHYDRATE METABOLISM IN DAIRY COWS AFTER CALVING DURING THE FORMATION OF …
Animal Effect of alfalfa hay and starter feed supplementation on caecal microbiota and fermentation, growth, and health of yak calves 33610512
Eur Rev Med Pharmacol Sci Salivary Irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients 33755963
Dig Dis Sci Orexin A Suppresses the Expression of Exosomal PD-L1 in Colon Cancer and Promotes T Cell Activity by Inhibiting JAK2/STAT3 Signaling Pathway 34097168
How Does the Th1/Th2 Polarization in Milk Change According to the Types of Bacteria that Cause Subclinical Mastitis in Cows?
World J Tradit Chin Med Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction via Th2 cytokine enhancement
Journal of Herbs, Spices & Medicinal Plants Immunostimulatory Effect of Moringa oleifera Extracts on Cyclophosphamide-induced Immunosuppressed Mice
Am J Transl Res Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma 34377237
J Immunol Res Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus 34395633
Experimental and Therapeutic Medicine Autonomic regulation of imbalance‑induced myocardial fibrosis and its mechanism in rats with cirrhosis 34373726
Viruses Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice 34960627
Animal Nutrition Optimizing the growth and immune system of dairy calves by subdividing the pre-weaning period and providing different milk volumes for each stage 34786502
Cancer Commun (Lond) Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancer Pubmed:34981670
Int J Mol Sci NLRP3 Inflammasome Activation Controls Vascular Smooth Muscle Cells Phenotypic Switch in Atherosclerosis Pubmed:35008765
Scientific Reports A randomized controlled trial evaluating the effect of two low-level laser irradiation protocols on the rate of canine retraction Pubmed:35710926
Experimental and Therapeutic Medicine Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis Pubmed:35126715
Toxicology Research Alleviation of chemotherapy-induced acute lung injury via NLRP3/ASC/Caspase-1 signaling pathway Pubmed:35782645
Vaccines Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated … Pubmed:35632433
Mljekarstvo Th1/Th2 cytokine polarization in milk according to different pathogens causing subclinical mastitis in cows
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APA073Hu01 Active Interleukin 2 (IL2) Cell culture; Activity Assays.
APA073Hu02 Active Interleukin 2 (IL2) Cell culture; Activity Assays.
EPA073Hu61 Eukaryotic Interleukin 2 (IL2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA073Hu01 Recombinant Interleukin 2 (IL2) Positive Control; Immunogen; SDS-PAGE; WB.
APA073Hu61 Active Interleukin 2 (IL2) Cell culture; Activity Assays.
RPA073Hu02 Recombinant Interleukin 2 (IL2) Positive Control; Immunogen; SDS-PAGE; WB.
PAA073Hu01 Polyclonal Antibody to Interleukin 2 (IL2) WB; IHC; FCM
PAA073Hu06 Polyclonal Antibody to Interleukin 2 (IL2) WB
FAA073Hu01 Anti-Interleukin 2 (IL2) Polyclonal Antibody FCM
LAA073Hu71 Biotin-Linked Polyclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC.
MAA073Hu26 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu21 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu22 Monoclonal Antibody to Interleukin 2 (IL2) WB
MAA073Hu24 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu25 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu23 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu27 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
MAA073Hu29 Monoclonal Antibody to Interleukin 2 (IL2) WB; IHC; ICC; IP.
HEA073Hu High Sensitive ELISA Kit for Interleukin 2 (IL2) Enzyme-linked immunosorbent assay for Antigen Detection.
MEA073Hu Mini Samples ELISA Kit for Interleukin 2 (IL2) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA073Hu ELISA Kit for Interleukin 2 (IL2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA073Hu CLIA Kit for Interleukin 2 (IL2) Chemiluminescent immunoassay for Antigen Detection.
LMA073Hu Multiplex Assay Kit for Interleukin 2 (IL2) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA073Hu01 ELISA Kit DIY Materials for Interleukin 2 (IL2) Main materials for "Do It (ELISA Kit) Yourself".