2021-09-28

CD3 is the best marker for detecting mature T cells in peripheral blood. Therefore, the determination of CD3 positive T cells is of great significance to the evaluation of immunodeficiency, such as T cell deficiency, leukemia, lymphoma and so on. In addition, the CD3 monoclonal antibody is fully utilized in immunosuppressive therapy during organ transplantation, bone marrow transplantation, and immunomodulatory therapy for the purpose of removing T cells for severe autoimmune diseases.2021-09-27

CD4+ T lymphocyte testing is an important indicator for evaluating the immune status of HIV-infected persons, predicting and judging the course of the disease, evaluating the effect of antiviral drug treatment, and estimating the prognosis. The World Health Organization (WHO), Europe and the United States and other countries recommend that people infected with HIV monitor the level of CD4+ T lymphocytes every 3-6 months, and use this indicator as a starting point to prevent interstitial plasma cell pneumonia and other opportunities Sexual infections, and as the main indicator of antiretroviral therapy.2021-09-27

Hepatocellular carcinomaHepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver cancers and ranks as the fourth most prevalent cancer worldwide. HCC primarily develops from hepatitis C virus infection, alcohol use, or nonalcoholic steatohepatitis (NASH) in North America and Europe; however, in eastern Asia and Africa, hepatitis B virus (HBV) infection is the predominant etiological factor. Regulatory T cellsRegulatory T cells (Treg) are a subset of T cells that control autoimmune reactivity in vivo. It has been a research hotspot in the field of immunology in recent years. Treg has the two major characteristics of low immune response and immunosuppression. Throug......2021-09-22

On 19 August, 2021, professor Di Yu from University of Queensland Diamantina Institute, professor Zheng Liu from Huazhong University of Science and Technology and professor Wenhong Zhang from Fudan University published a paper titled Selenium‒GPX4 axis protects follicular helper T cells from ferroptosis on Nature Immunology. Follicular helper T (TFH) cells are a specialized subset of CD4+ T cells that essentially support germinal center responses where high-affiffiffinity and long-lived humoral immunity is generated. The regulation of TFH cell survival remains unclear. Here we report that TFH cells show intensifified lipid peroxidation and altered mitochondrial morphology, resembling......2021-09-07

In August. 2021, Literature of Cloud Clone products has exceeded 210. Cloud-Clone could provide multipleproteins, antibodies and ELISA kit, which has been praised by customers.2021-08-30