In August 2022,Wanhai Xu, Department of Urology, the Fourth Hospital of Harbin Medical University, China, and his team published a paper titled “Bacteria-inspired transformable nanoparticle targets and covers residual tumor against bladder cancer recurrence” in Nano Today, which provided a promising intravesical treatment but also opportunities for clinical management on cancer recurrence.The kits [ELISA Kit for Fibronectin (FN), SEA037Hu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.The regrowth of residual tumor left by incomplete surgery leads to bladder cancer recurrence. Postoperative intravesical instillation in clinic shows ......2022-08-10

Pancreatitis is a gastrointestinal disorder with considerable morbidity and mortality. Acute pancreatitis, recurrent acute pancreatitis, and chronic pancreatitis form a disease continuum. Some factors causing these diseases include alcohol, bile acids, and ductal obstruction, where they induce the inflammatory response that promotes their pathogenesis. Common cellular events underlying the pathogenesis of acute pancreatitis include increased oxidative stress, premature intra-acinar trypsinogen activation, activated calcium signaling, mitochondrial dysfunction, endoplasmic reticulum stress, and autophagy impairment. Recently, several articles have reported new insights into the mechanis......2022-08-08

On June 29, 2022,N. Altan-Bonnet, Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, USA, and his team published a paper titled “Enteric viruses replicate in salivary glands and infect through saliva” in Nature, which uncovered a new transmission route for enteric viruses.The kits [ELISA Kit for Secretory Immunoglobulin A (sIgA), SEA641Mu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Enteric viruses like norovirus, rotavirus and astrovirus have long been accepted as spreading in the population through fecal–oral transmission: viruses are shed into feces from one host and ......2022-08-05

Malaria is a deadly infectious disease, caused by protist parasites of the genus Plasmodium,that affects 241 million people worldwide. Current antimalarial treatments are rapidly losing efficacy, and standard-of-care artemisinin combination therapies fail to cure infections in ~50% of patients in some regions of Asia. Clinically validated resistance to artemisinins has now been detected in Africa, where most malaria deaths occur. New treatments with novel modes of action are urgently needed to overcome existing resistance, expand possible treatment options, and enable more effective combination therapies. 1. Activation of cGAS-STING by Lethal Malaria N67C Dictates Immunity and Mortalit......2022-08-05

Diabetes is a tremendous health problem worldwide. It is caused by chronic high glucose levels in the blood as a result of the incapability of β cells in the pancreas to produce adequate insulin or ineffective insulin utilization by cells in the body. There are generally 3 types of diabetes: Type I, II and gestationaldiabetes but more emphasis is placed on the first 2 types of diabetes.As a chronic condition, diabetes tends to increase the risk of several other diseases caused by macrovascular and microvascular damage, and it has negative impacts on several organs, such as the brain, kidney, heart, and eyes. In addition, diabetic patients are more susceptible to infection. Recently, a......2022-07-22

On 16 June 2022, Xiangming Mao, Department of Urology, Zhujiang Hospital, Southern Medical University, China, and his team published a paper titled “Gut dysbiosis promotes prostate cancer progression anddocetaxel resistance viaactivating NF-κB-IL6-STAT3 axis” in Microbiome, which demonstrated that gut dysbiosis resulted in the elevation of gut permeability and intratumoral LPS, promoting the development of prostate cancer via the NF-κB-IL6-STAT3 axis in mice.The antibodies [Monoclonal Antibody to Lipopolysaccharide (LPS), MAB526Ge22]and kits [ELISA Kit for Lipopolysaccharide (LPS), SEB526Ge]of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaser......2022-07-20