Recombinant Antibody to Interleukin 4 (IL4)

BSF1; BCGF1 ;B Cell Stimulatory Factor 1; Lymphocyte stimulatory factor 1; B Cell Growth Factor; Binetrakin; Pitrakinra

  • Product No.RAA077Hu21
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceRecombinant monoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype mouse IgG2b Kappa
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IF; ICC; IHC; IP; FCM.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 171  US$ 399  US$ 570  US$ 1425  US$ 5700 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against IL4. It has been selected for its ability to recognize IL4 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
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Molecular Biology Reports Dexamethasone attenuates development of monocrotaline-induced pulmonary arterial hypertension SpringerLink: 76255j50271l4nh2
6th International Scientific Interdisciplinary Conference (ISIC) Inflammation influence on the formation of endothelial dysfunction in hypertensive patients caused by obesity Knmu: Source
Theriogenology Evaluation of serum concentrations of interleukin (IL)-4, IL-10, and IL-12 during pregnancy in bitches ScienceDirect: S0093691X1300037X
International Journal of Poultry Science Immune Responses to Eimeria tenella Sporozoite Protein as Vaccine to Broiler Against Coccidiosis Pjbs: Source
European Journal of Pharmacology Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice Pubmed: 23792144
Journal of Dairy Science Increased blood-circulating interferon-γ, interleukin-17, and osteopontin levels in bovine paratuberculosis Pubmed:24679935
Biomedical Research The toxic effect of nickel nanoparticles on oxidative stress and inflammatory markers. Articles:
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Immunologic Research Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE3 and is crucial for liver transplant tolerance PubMed: 25982496
J Reprod Immunol The immunomodulating effect of seminal plasma on T cells PubMed: 25799173
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удк Циток Cgi-Bin: Irbis_Nbuv
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Virol J Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4 PubMed: 26573719
Int J Clin Exp Pathol Downregulation of SUMF2 gene in ovalbumin-induced rat model of allergic inflammation PubMed: 26722390
Infection, Genetics and Evolution Infection of chicken bone marrow mononuclear cells with subgroup J avian leukosis virus inhibits dendritic cell differentiation and alters cytokine expression Pubmed:27349993
Plos One Immunopotentiators Improve the Efficacy of Oil-Emulsion-Inactivated Avian Influenza Vaccine in Chickens, Ducks and Geese Pubmed:27232188
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Mediators Inflamm Proinflammatory and Anti-Inflammatory Cytokines Mediated by NF-ÎşB Factor as Prognostic Markers in Mammary Tumors Pubmed:26989335
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Molecular Immunology Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma pubmed:27289030
Basrah Journal of Veterinary Research EVALUATION OF HUMORAL AND CELLULAR IMMUNE RESPONSES TO EIMERIA TENELLA OOCYST PROTEIN AS VACCINE TO BROILER 363-379.pdf
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Journal of Virology Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed:
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Gut Pathog. Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice pubmed:28250847
Veterinary Immunology and Immunopathology Cytokine levels in colostrum and in foals' serum pre- and post-suckling pubmed:28242000
Journal of Agricultural and Food Chemistry Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathway pubmed:29032684
Bulgarian Journal of Veterinary Medicine COMPARATIVE EFFICACY OF TWO HETEROLOGOUS CAPRIPOX VACCINES TO CONTROL LUMPY SKIN DISEASE IN CATTLE ISSN 1311-1477
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs pubmed:28549299
Scientific Report Anti-asthmatic efect of pitavastatin through aerosol inhalation is associated with CD4+ CD25+ Foxp3+ T cells in an asthma mouse model pubmed:28729731
Austral journal of veterinary sciences The effects of Spirulina platensis (Arthrospira platensis) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T … S0719-81322017000300185
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Scientific Report Stress Induced Polarization of Immune-Neuroendocrine Phenotypes in Gallus gallus pubmed:28808318
Frontiers in Immunology Single dose of consensus hemagglutinin-based virus-like particles vaccine protects chickens against divergent H5 subtype influenza viruses pubmed:29230222
Microbiology Antigen-Sparing and Enhanced Efficacy of Multivalent Vaccines Adjuvanted with Immunopotentiators in Chickens pubmed:28603519
Asian Pacific Society of Respirology Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice pubmed:28122397
Nutrition Administration of probiotic mixture DM#1 ameliorated 5-fluorouracil-induced intestinal mucositis and dysbiosis in rats pubmed:27427511
Journal of Dairy Science Milk and serum IL-4, IL-6, IL-10, and amyloid A concentrations in cows with subclinical mastitis caused by coagulase-negative staphylococci pubmed:28964518
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-ݜ傠Signaling Pathway in Rats 10.1155/2017/3057268
Oncotarget The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis. pubmed:29029533
Scientific Reports Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets pubmed:28811665
Biological Rhythm Research A study of altered cytokine rhythms associated with successful implantation in cows 10.1080/09291016.2017.1361159
Journal of Pain Research Sex differences in complex regional pain syndrome type I (CRPS-I) in mice pubmed:28831269
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats 10.1155/2017/3057268
Journal of Thoracic Oncology Systemic and Tumor Th1 and Th2 Inflammatory Profile and Macrophages in Lung Cancer: Influence of Underlying Chronic Respiratory Disease. pubmed:27793775
Journal of Autoimmunity Commensal bacteria aggravate allergic asthma via NLRP3/IL-1β signaling in post-weaning mice 10.1016:j.jaut.2018.07.003
Scientific Reports A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling Pubmed:29523851
Metallomics Selenium deficiency inhibits differentiation and immune function and imbalances the Th1/Th2 of dendritic cells Pubmed:29766201
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PLoS One Chitosan oligosaccharide ameliorates acute lung injury induced by blast injury through the DDAH1/ADMA pathway Pubmed:29415054
Biomed Research International Epstein Barr Virus Infection Affects Function of Cytotoxic T Lymphocytes in Patients with Severe Aplastic Anemia Pubmed:29862282
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … Pubmed:29305686
Medical Science Monitor Involvement of T-Helper 9 Activation in a Mouse Model of Allergic Rhinitis Pubmed:29982264
Acta veterinaria Hungarica Analysis of the immune response of calves to various saponin-based adjuvants for an experimental vaccine Pubmed:29958518
Journal of Integrative Agriculture Construction of Pullorum ghost by co-expression of lysis gene E and the antimicrobial peptide SMAP29 and evaluation of its immune efficacy in specific … 10.1016:S2095-3119(17)61696-4
Journal of International Medical Research Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease Pubmed:29950127
Iranian Journal of Veterinary Science and Technology Immune response characteristics of Capri pox virus vaccines following emergency vaccination of cattle against lumpy skin disease virus 65381
خصوصیات پاسخ‌های ایمنی القاء شده ناشی از واکسن زنده تخفیف حدت یافته آبله بزی سویه گرگان بر علیه بیماری لمپی اسکین در گاو‎
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International Journal of Peptide Research and Therapeutics ANP/NPRA Inhibits Epithelial-Mesenchymal Transition of Airway by Targeting Smad3 in Asthma
Pharmacological Reports Protective effects of polydatin in free and nanocapsulated form on changes caused by lipopolysaccharide in hippocampal organotypic cultures
Royal Society Open Science Metabolomics analysis of baicalin on ovalbumin-sensitized allergic rhinitis rats
Viruses Construction and Immunogenicity of Novel Chimeric Virus-Like Particles Bearing Antigens of Infectious Bronchitis Virus and Newcastle Disease Virus Pubmed: 30871190
Scientific Reports Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice Pubmed: 30962497
Frontiers in Microbiology Local probiotic Lactobacillus crispatus and Lactobacillus delbrueckii exhibit strong antifungal effects against vulvovaginal candidiasis in a rat model
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Nutrients Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats Pubmed: 31887996
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