Monoclonal Antibody to Glutathione Peroxidase 4 (GPX4)

MCSP; PHGPx; SnGPx; SnPHGPx; Phospholipid Hydroperoxidase; Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

SPECIFITY

The antibody is a mouse monoclonal antibody raised against GPX4. It has been selected for its ability to recognize GPX4 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Biomedicine & Pharmacotherapy Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway Pubmed: 30551460
Acta Biomater An all-in-one biomimetic iron-small interfering RNA nanoplatform induces ferroptosis for cancer therapy Pubmed:35709941
Antioxidants Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis Pubmed:35204181
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