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Monoclonal Antibody to Hemojuvelin (HJV)

HFE2; HFE2A; HJV; JH; RGMC; hemochromatosis type 2(Juvenile); Haemojuvelin; RGM domain family member C

  • Product No.MAB995Ra21
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 115  US$ 267  US$ 382  US$ 955  US$ 3820 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against HJV. It has been selected for its ability to recognize HJV in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
PLoS One. Effect of Iron Overload and Iron Deficiency on Liver Hemojuvelin Protein PubMed: PMC3356351
Journal of Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary Report PubMed: 25881778
European Journal of Haematology Soluble hemojuvelin in transfused and untransfused thalassaemic subjects doi:10.1111
American Journal of Nephrology The secret war against counterfeit science pubmed:28492262
Critical Care Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery Pubmed:29699579
Scientific Reports Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery Pubmed:29386545
Journal of Cerebral Blood Flow and Metabolism The functional role of hemojuvelin in acute ischemic stroke Pubmed: 31307288
Oxidative damage and iron dyshomeostasis in thalassemic patients
J Trace Elem Med Biol Caffeine and alcohol-friends or foes of human iron stores? Pubmed:35063815
Arch Pathol Lab Med Urinary Biomarkers Can Predict Weaning From Acute Dialysis Therapy in Critically Ill Patients Pubmed:35311928
Arch Pathol Lab Med The Relationships among Plasma Fetuin-B, Thyroid Autoimmunity, and Fertilization Rate In Vitro Fertilization and Embryo Transfer Pubmed:35340679
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB995Ra01 Recombinant Hemojuvelin (HJV) Positive Control; Immunogen; SDS-PAGE; WB.
PAB995Ra01 Polyclonal Antibody to Hemojuvelin (HJV) WB; IHC; ICC; IP.
MAB995Ra21 Monoclonal Antibody to Hemojuvelin (HJV) WB; IHC; ICC; IP.
SEB995Ra ELISA Kit for Hemojuvelin (HJV) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB995Ra Multiplex Assay Kit for Hemojuvelin (HJV) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSB995Ra01 ELISA Kit DIY Materials for Hemojuvelin (HJV) Main materials for "Do It (ELISA Kit) Yourself".