≡

Monoclonal Antibody to Neuregulin 1 (NRG1)

ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor

  • Product No.MAB866Hu27
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 107  US$ 250  US$ 357  US$ 893  US$ 3570 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against NRG1. It has been selected for its ability to recognize NRG1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Neuroscience Letter Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom Cyagen: source
PLoS One. ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis PubMed: PMC3519469
The Journal of Clinical Investigation Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration PubMed: PMC3428100
Physiol Behav Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress PubMed: 26626816
J Toxicol Sci.  Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. Pubmed:26961615
journal of cellular and molecular medicine Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. pubmed:28271613
Transl Psychiatry. Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. pubmed:28267150
Human Molecular Genetics A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas Pubmed: 30335132
Aging (Albany NY) Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin Pubmed: 32920546
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APB866Hu01 Active Neuregulin 1 (NRG1) Cell culture; Activity Assays.
RPB866Hu01 Recombinant Neuregulin 1 (NRG1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB866Hu01 Polyclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
LAB866Hu71 Biotin-Linked Polyclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC.
MAB866Hu25 Monoclonal Antibody to Neuregulin 1 (NRG1) WB
MAB866Hu27 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu22 Monoclonal Antibody to Neuregulin 1 (NRG1) WB
MAB866Hu21 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu23 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu24 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
SEB866Hu ELISA Kit for Neuregulin 1 (NRG1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB866Hu Multiplex Assay Kit for Neuregulin 1 (NRG1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSB866Hu01 ELISA Kit DIY Materials for Neuregulin 1 (NRG1) Main materials for "Do It(ELISA Kit) Yourself"