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Monoclonal Antibody to Neuregulin 1 (NRG1)

ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor

SPECIFITY

The antibody is a mouse monoclonal antibody raised against NRG1. It has been selected for its ability to recognize NRG1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Neuroscience Letter Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom Cyagen: source
PLoS One. ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis PubMed: PMC3519469
The Journal of Clinical Investigation Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration PubMed: PMC3428100
Physiol Behav Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress PubMed: 26626816
J Toxicol Sci.  Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. Pubmed:26961615
journal of cellular and molecular medicine Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. pubmed:28271613
Transl Psychiatry. Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. pubmed:28267150
Human Molecular Genetics A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas Pubmed: 30335132
Aging (Albany NY) Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin Pubmed: 32920546
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APB866Hu01 Active Neuregulin 1 (NRG1) Cell culture; Activity Assays.
RPB866Hu01 Recombinant Neuregulin 1 (NRG1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB866Hu01 Polyclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
LAB866Hu71 Biotin-Linked Polyclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC.
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MAB866Hu27 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu22 Monoclonal Antibody to Neuregulin 1 (NRG1) WB
MAB866Hu21 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu23 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
MAB866Hu24 Monoclonal Antibody to Neuregulin 1 (NRG1) WB; IHC; ICC; IP.
SEB866Hu ELISA Kit for Neuregulin 1 (NRG1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB866Hu Multiplex Assay Kit for Neuregulin 1 (NRG1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSB866Hu01 ELISA Kit DIY Materials for Neuregulin 1 (NRG1) Main materials for "Do It(ELISA Kit) Yourself"