Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)

HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor

Product No.MAB479Hu24
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourceMonoclonal antibody preparation
HostMouse
Potency (Clone Number)C1
Ig Isotype IgG1 Kappa
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPB479Hu01-Recombinant Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid
Concentration1mg/mL
Organism Species MoreSus scrofa; Porcine (Pig)
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
DownloadInstruction Manual
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 93 217 US$ 217 US$ 310 US$ 775 US$ 3100
For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against HBEGF. It has been selected for its ability to recognize HBEGF in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine	Citations
Neuropathology	Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling. PubMed: 21118399
Toxicological Sciences	Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling Pubmed: source
PAIN RESEARCH	軽度炎症性膀胱痛マウスモデルの構築とNGFの関与 Jstage:Source
European Journal of Pain	A novel method for assessing bladder-related pain reveals the involvement of nerve growth factor in painassociated with cyclophosphamide-induced chronic cystitis in mice. Pubmed:25820250
Kinki daigaku	2 型糖尿病モデルラットにおける糖尿病性腎症の進行とHB-EGF の関連性 17844
laboratory investigation	Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition Pubmed:29581578
International Journal of Biological Sciences	CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17
Redox Biology	Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Pubmed: 30769285
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE	Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets Pubmed: 33164313
	象牙芽細胞の枯渇は象牙芽細胞分化と象牙質形成を誘導する

Catalog No.	Related products for research use of Homo sapiens (Human) Organism species	Applications (RESEARCH USE ONLY!)
APB479Hu01	Active Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Cell culture; Activity Assays.
APB479Hu61	Active Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Cell culture; Activity Assays.
EPB479Hu61	Eukaryotic Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB479Hu01	Recombinant Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Positive Control; Immunogen; SDS-PAGE; WB.
PAB479Hu01	Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB,IHC
LAB479Hu71	Biotin-Linked Polyclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC.
MAB479Hu22	Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC; IP.
MAB479Hu25	Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC; IP.
MAB479Hu21	Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC; IP.
MAB479Hu23	Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC; IP.
MAB479Hu24	Monoclonal Antibody to Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	WB; IHC; ICC; IP.
SEB479Hu	ELISA Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Enzyme-linked immunosorbent assay for Antigen Detection.
SCB479Hu	CLIA Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)	Chemiluminescent immunoassay for Antigen Detection.
LMB479Hu	Multiplex Assay Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.