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Monoclonal Antibody to Inducible T-Cell Co Stimulator (ICOS)

CD278; AILIM; Inducible T-Cell Costimulator; Activation-Inducible Lymphocyte Immunomediatory Molecule

  • Product No.MAA777Hu22
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 101  US$ 235  US$ 336  US$ 840  US$ 3360 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against ICOS. It has been selected for its ability to recognize ICOS in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Archives of Dermatological Research Increased production of soluble inducible costimulator in patients with diffuse cutaneous systemic sclerosis Pubmed: 23053221
DNA Cell Biol. Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration. Pubmed: 24083358
Rheumatology Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis Pubmed: 23024058
Br J Haematol Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment Pubmed:34954822
Diagnostics (Basel) Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases Pubmed:35328257
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA777Hu01 Recombinant Inducible T-Cell Co Stimulator (ICOS) Positive Control; Immunogen; SDS-PAGE; WB.
PAA777Hu01 Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC; IP.
FAA777Hu01 Anti-Inducible T-Cell Co Stimulator (ICOS) Polyclonal Antibody Flow cytometry.
LAA777Hu81 FITC-Linked Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC; IF.
LAA777Hu71 Biotin-Linked Polyclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC.
FAA777Hu41 PE-Linked Anti-Inducible T-Cell Co Stimulator (ICOS) Polyclonal Antibody Flow cytometry.
FAA777Hu51 APC-Linked Anti-Inducible T-Cell Co Stimulator (ICOS) Polyclonal Antibody Flow cytometry.
FAA777Hu81 FITC-Linked Anti-Inducible T-Cell Co Stimulator (ICOS) Polyclonal Antibody Flow cytometry.
MAA777Hu22 Monoclonal Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IHC; ICC; IP.
RAA777Hu21 Recombinant Antibody to Inducible T-Cell Co Stimulator (ICOS) WB; IFC; IHC; IP.
SEA777Hu ELISA Kit for Inducible T-Cell Co Stimulator (ICOS) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA777Hu Multiplex Assay Kit for Inducible T-Cell Co Stimulator (ICOS) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.