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FITC-Linked Polyclonal Antibody to Permeability Glycoprotein (Pgp)

CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin Sensitivity

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against Pgp. It has been selected for its ability to recognize Pgp in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
International Forum of Allergy & Rhinology P-glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polyps Onlinelibrary: alr.21316
International Forum of Allergy & Rhinology P‐glycoprotein regulates Staphylococcus aureus enterotoxin B–stimulated interleukin‐5 and thymic stromal lymphopoietin secretion in organotypic mucosal explants PubMed: 26625351
American Journal of Rhinology & Allergy Intact soluble P-glycoprotein is secreted by sinonasal epithelial cells. pubmed:27456593
The Laryngoscope Secreted P-glycoprotein is a noninvasive biomarker of chronic rhinosinusitis pubmed:27577924
Materials Science and Engineering: C Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia
Molecular Cancer Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance Pubmed: 31830995
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