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Lysine Specific Demethylase 1A (KDM1A)

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AOF2; KDM1; BHC110; LSD1; Amine Oxidase Flavin Containing Domain 2; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

Lysine Specific Demethylase 1A (KDM1A)
CCC G802
HGNC 29079
MGI 1196256
PubMed 22406747
RGD 1562975
UniProt O60341
Posttranslational modifications of histone N-terminal tails, including methylation, impact chromatin structure and gene transcription. KDM1A functions as a histone demethylase and transcriptional corepressor.
The deduced protein contains 886 amino acids. RT-PCR detected expression of KDM1A in nearly all tissues tested, with highest levels in kidney and testis. Little to no expression was detected in pancreas and spleen.LSD1, has an N-terminal SWIRM domain, which is found in proteins involved in chromatin regulation, followed by a FAD-binding motif and an amine oxidase domain. By searching for proteins with both amine oxidase and SWIRM domains, they identified AOF1 (KDM1B) as a human LSD1-like protein, as well as several LSD1-like proteins in C. elegans, Drosophila, Arabidopsis, and S. pombe.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 1A (KDM1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 1A (KDM1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 1A (KDM1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 1A (KDM1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 1A (KDM1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 1A (KDM1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 1A (KDM1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 1A (KDM1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 1A (KDM1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 1A (KDM1A) ELISA Kit Customized Service Offer
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